Results 61 to 70 of about 365 (231)

Pseudo-Sasakian manifolds endowed with a contact conformal connection

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1986
Pseudo-Sasakian manifolds M˜(U,ξ,η˜,g˜) endowed with a contact conformal connection are defined.
Vladislav V. Goldberg, Radu Rosca
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Hierarchy of spaces of projective connection

open access: yesДифференциальная геометрия многообразий фигур, 2018
We consider the bundle of projective frames over a smooth manifold, i. e. the principal bundle whose typical fiber is the projective group. The giving fundamental-group connection in this bundle transforms it into a space of general projective connection.
Yu. Shevchenko
doaj  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Defining the mobility range of a hinge-type connection using molecular dynamics and metadynamics.

open access: yesPLoS ONE, 2020
A designed disulfide-rich β-hairpin peptide that dimerizes spontaneously served as a hinge-type connection between proteins. Here, we analyze the range of dynamics of this hinge dimer with the aim of proposing new applications for the DNA-encodable ...
Philip Horx, Armin Geyer
doaj   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

About an analogue of Neifeld’s connection on the space of centred planes with one-index basic-fibre forms

open access: yesДифференциальная геометрия многообразий фигур, 2019
This research is realized by Cartan — Laptev method (with prolonga­tions and scopes, moving frame and exterior forms). In this paper we con­sider a space П of centered m-planes (a space of all centered planes of the dimension m). This space is considered
Е. Belova, O. Belova
doaj   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

open access: yesMolecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche   +8 more
wiley   +1 more source

General Relativity with a Positive Cosmological Constant Λ as a Gauge Theory

open access: yesAxioms, 2019
In this paper, we show that the general relativity action (and Lagrangian) in recent Einstein⁻Palatini formulation is equivalent in four dimensions to the action (and Langrangian) of a gauge field.
Marta Dudek, Janusz Garecki
doaj   +1 more source

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