Results 81 to 90 of about 292,639 (308)

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Hierarchy of spaces of projective connection

open access: yesДифференциальная геометрия многообразий фигур, 2018
We consider the bundle of projective frames over a smooth manifold, i. e. the principal bundle whose typical fiber is the projective group. The giving fundamental-group connection in this bundle transforms it into a space of general projective connection.
Yu. Shevchenko
doaj  

Connections on a parabolic principal bundle, II [PDF]

open access: yesarXiv, 2007
In \cite{Bi2} (Canad. Jour. Math. Vol. 58) we defined connections on a parabolic principal bundle. While connections on usual principal bundles are defined as splittings of the Atiyah exact sequence, it was noted in \cite{Bi2} that the Atiyah exact sequence does not generalize to the parabolic principal bundles.
arxiv  

Invariant Yang-Mills connections over Non-Reductive Pseudo-Riemannian Homogeneous Spaces

open access: yes, 2008
We study invariant gauge fields over the 4-dimensional non-reductive pseudo-Riemannian homogeneous spaces G/K recently classified by Fels & Renner (2006).
The, Dennis
core   +2 more sources

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

About an analogue of Neifeld’s connection on the space of centred planes with one-index basic-fibre forms

open access: yesДифференциальная геометрия многообразий фигур, 2019
This research is realized by Cartan — Laptev method (with prolonga­tions and scopes, moving frame and exterior forms). In this paper we con­sider a space П of centered m-planes (a space of all centered planes of the dimension m). This space is considered
Е. Belova, O. Belova
doaj   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

General Relativity with a Positive Cosmological Constant Λ as a Gauge Theory

open access: yesAxioms, 2019
In this paper, we show that the general relativity action (and Lagrangian) in recent Einstein⁻Palatini formulation is equivalent in four dimensions to the action (and Langrangian) of a gauge field.
Marta Dudek, Janusz Garecki
doaj   +1 more source

Local connection forms revisited

open access: yes, 2013
Local connection forms provide a very useful tool for handling connections on principal bundles, because they ignore any complexities of the total space and, essentially, involve only two fundamental features of the structure group, namely the adjoint ...
Vassiliou, Efstathios
core   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

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