Results 81 to 90 of about 5,540 (286)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu +10 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano +11 more
wiley +1 more source
Five-dimensional Kaluza-Klein Theory reformulated
Revista Técnica de la Facultad de Ingeniería, 2011 This paper presents a reformulation of the five-dimensional Kaluza-Klein theory. taking into consideration the fact that these five dimensions of space-time are present on the tangent bundle of the Principal Bundle (B). Tb1s reformulation is possible due
Williams Pitter, Mario Choy
doaj
On the Invariant and Geometric Structure of the Holomorphic Unified Field Theory
AxiomsWe present the invariant structure of a Holomorphic Unified Field Theory in which gravity and gauge interactions arise from a single geometric framework.
John W. Moffat, Ethan James Thompson
doaj +1 more source
Algebra of Principal Fibre Bundles, and Connections
, 2000 We put together some of the efforts by several people of making aspects of fibre bundle theory into algebra. The initiator of these efforts was Charles Ehresmann, who put the notion of groupoid and groupoid action in the focus of fibre bundle theory in general, and in connection theory in particular.
openaire +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling +16 more
wiley +1 more source
Connections on a Principal Lie Groupoid Bundle and Representations Upto Homotopy [PDF]
Saikat Chatteerjee, Naga Arjun S J
openalex +2 more sources
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source