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Nailfold capillaroscopy in rheumatic connective tissue diseases [PDF]

open access: yesRheumatology
Capillaroscopy is a non-invasive examination used for imaging of capillary vessels of the papillary layer of the finger nailfold. It allows the detection of microcirculation disorders in systemic connective tissue diseases.
Ewa Wielosz, Natalia Siedlecka
doaj   +2 more sources

Connective Tissue and Fibroblast Senescence in Skin Aging.

open access: yesJournal of Investigative Dermatology, 2021
There is increasing evidence that skin aging is significantly enforced by the accumulation of senescent dermal fibroblasts. Various stressors damaging macromolecules inside and outside fibroblasts are responsible. In addition, NK cells fail to adequately
M. Wlaschek   +3 more
semanticscholar   +1 more source

The impact of collagen protein ingestion on musculoskeletal connective tissue remodeling: a narrative review

open access: yesNutrition reviews, 2021
Collagen is the central structural component of extracellular connective tissue, which provides elastic qualities to tissues. For skeletal muscle, extracellular connective tissue transmits contractile force to the tendons and bones.
A. Holwerda, L. V. van Loon
semanticscholar   +1 more source

Safety of liver function monitoring every 3 months in patients treated with low dose methotrexate [PDF]

open access: yesJournal of Analytical Research in Clinical Medicine, 2014
Introduction: The objective of this study was to evaluate the safety of liver transaminases monitoring every 12 weeks in patients with inflammatory connective tissue disorders who aretreated with methotrexate (MTX). Methods: In a retrospective study, the
Alireza Khabbazi   +11 more
doaj   +1 more source

Combinations of scleroderma hallmark autoantibodies associate with distinct clinical phenotypes

open access: yesScientific Reports, 2022
Systemic sclerosis (SSc) is characterized by the presence of SSc-specific or SSc-associated antibodies (SSc-Abs): anti-topoisomerase I (ATA), anti-centromere (ACA), anti-RNA polymerase III (ARA), anti-U3RNP (U3RNP), anti-U1RNP (U1RNP), anti-PmScl (PmScl),
Kristina E. N. Clark   +6 more
doaj   +1 more source

Cold intolerance and associated factors: a population study

open access: yesScientific Reports, 2022
Cold intolerance has been defined as a set of symptoms including pain, tingling, numbness, chills, stiffness, weakness, swelling or skin color changes on exposure to cold. Cold intolerance may have a profound effect on health-related quality of life.
Alireza Khabbazi   +8 more
doaj   +1 more source

The prevalence and significance of anti-PM/Scl antibodies in systemic sclerosis

open access: yesAnnals of Agricultural and Environmental Medicine, 2021
Introduction Anti-PM/Scl (a-PM/Scl) antibodies are found in different systemic autoimmune diseases such as polymyositis, dermatomyositis, systemic sclerosis (SSc) and overlap syndromes. According to literature, they are detected in approx.
Ewa Wielosz   +2 more
doaj   +1 more source

The pan-PPAR agonist lanifibranor reduces development of lung fibrosis and attenuates cardiorespiratory manifestations in a transgenic mouse model of systemic sclerosis

open access: yesArthritis Research & Therapy, 2021
Background The TβRII∆k-fib transgenic (TG) mouse model of scleroderma replicates key fibrotic and vasculopathic complications of systemic sclerosis through fibroblast-directed upregulation of TGFβ signalling.
Emma Derrett-Smith   +10 more
doaj   +1 more source

Hypoparathyroidism as one of the initial presentations of systemic lupus erythematosus

open access: yesClinical Case Reports, 2022
Systemic lupus erythematosus (SLE) is an autoimmune disease and may be associated with many autoimmune conditions. Hypoparathyroidism is a rare disease. The leading cause of hypoparathyroidism is postsurgical hypoparathyroidism.
Leyla Gadakchi   +4 more
doaj   +1 more source

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