Results 11 to 20 of about 2,252,458 (304)

Heritable Connective Tissue Disorders in Childhood: Increased Fatigue, Pain, Disability and Decreased General Health [PDF]

open access: yes, 2021
Heritable Connective Tissue Disorders (HCTD) show an overlap in the physical features that can evolve in childhood. It is unclear to what extent children with HCTD experience burden of disease.
Alsem, Mattijs W.   +57 more
core   +2 more sources

Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients [PDF]

open access: yes, 2001
Patients with scleroderma receiving Iloprost as a treatment for severe Raynaud's phenomenon report a reduction in skin tightness, suggesting that this drug inhibits skin fibrosis.
Stratton, R   +27 more
core   +1 more source

Effect of Nigella sativa oil extracts on inflammatory and oxidative stress markers in Behcet’s disease: A randomized, double-blind, placebo-controlled clinical trial [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2020
Objective: Behcet's disease (BD) is a chronic inflammatory disorder characterized by recurrent oral and genital aphthous ulcers, uveitis and skin lesions. Oxidative stress and inflammation have important role in the pathogenesis of BD.
Shahrzad Amizadeh   +7 more
doaj   +1 more source

Connective tissue ulcers [PDF]

open access: yesJournal of Tissue Viability, 2013
Connective tissue disorders (CTD), which are often also termed collagen vascular diseases, include a number of related inflammatory conditions. Some of these diseases include rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis (scleroderma), localized scleroderma (morphea variants localized to the skin), Sjogren's syndrome ...
Ganary, Dabiri, Vincent, Falanga
openaire   +2 more sources

Comparison of International Study Group Criteria and International Criteria for Behcet's Disease in the Azeri population of Iran [PDF]

open access: yesJournal of Analytical Research in Clinical Medicine, 2017
Introduction: Behcet's disease (BD) is a chronic systemic inflammatory disease affecting multiple organs and systems such as mucosa, skin, eye, joints and cardiovascular, nervous and gastrointestinal systems. Various criteria are proposed for
Leila Delnabi   +4 more
doaj   +1 more source

Nitric oxide modulates expression of extracellular matrix genes linked to fibrosis in kidney mesangial cells [PDF]

open access: yes, 2007
Mesangial cells are thought to be important mediators of glomerular inflammation and fibrosis. Studies have established a direct role for nitric oxide (NO) in the regulation of gene expression in mesangial cells.
Nelson, Peter J.   +4 more
core   +1 more source

Microangiopathic antiphospholipid syndrome (MAPS) in the course of undifferentiated connective tissue disease

open access: yesJournal of Medical Science, 2014
Introduction. The microangiopathic antiphospholipid syndrome (MAPS) is a subset of APS comprising those patients presenting with thrombotic microangiopathy and demonstrable antiphospholipid antibodies. Renal involvement occurs frequently in the course of
Bożena Targońska-Stępniak   +2 more
doaj   +1 more source

Prospective assessment of cardiovascular risk parameters in patients with rheumatoid arthritis

open access: yesCardiovascular Ultrasound, 2018
Background The study presents a prospective follow-up assessment of cardiovascular (CV) risk parameters in patients with rheumatoid arthritis (RA) in comparison with control subjects. Methods The study group consisted of 41 RA patients.
Bożena Targońska-Stępniak   +4 more
doaj   +1 more source

Exploring metabolism in scleroderma reveals opportunities for pharmacological intervention for therapy in fibrosis

open access: yesFrontiers in Immunology, 2022
BackgroundRecent evidence has indicated that alterations in energy metabolism play a critical role in the pathogenesis of fibrotic diseases. Studies have suggested that ‘metabolic reprogramming’ involving the glycolysis and oxidative phosphorylation ...
Isabella Gomes Cantanhede   +14 more
doaj   +1 more source

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