Results 41 to 50 of about 587,613 (311)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Globule leukocytes and mast cells in the rat trachea: their number, distribution, and response to compound 48/80 and dexamethasone. [PDF]

, 1988
Globule leukocytes in the epithelium of the rat trachea may be counterparts of mucosal mast cells that are located in the gastrointestinal tract. If they are indeed similar to mucosal mast cells, globule leukocytes would be expected to decrease in number
Calonico, LD, McDonald, DM, Nadel, JA, Tam, EK   +3 more
core  

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

In vivo characterization of connective tissue remodeling using infrared photoacoustic spectra [PDF]

, 2018
Premature cervical remodeling is a critical precursor of spontaneous preterm birth, and the remodeling process is characterized by an increase in tissue hydration.
Alisio, Mariana, Altieri, Emma, Anderson, Monica, Barber, Sabrina, Burger, Tracy, Chubiz, Jessica, Diveley, Emily, England, Sarah K, Garcia-Uribe, Alejandro, Goldstein, Naomi, Helm, Kristi, Hu, Peng, Kramer, Christine, Li, Chiye, Ma, Jun, Macones, George A, Maslov, Konstantin, Maynard, Jennifer, McCarthy, Ronald, Meyenburg, Kaytelyn, Meyers, Karen, Muench, Lisa, Onwumere, Oji, Pizzella, Stephanie, Punyamurthy, Nina, Qu, Yuan, Shi, Junhui, Slaughter, Janessia, Stout, Molly J, Tuuli, Methodius, Wang, Lihong V, Zhao, Peinan   +31 more
core   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source

Eosinophilic granulomatosis with polyangiitis following flu guard influenza vaccination: A case report

Clinical Case Reports, 2023
Key Clinical Message This case highlights a potential association between influenza vaccination and the development of eosinophilic granulomatosis with polyangiitis (EGPA), prompting the need for increased vigilance regarding vaccine‐related autoimmune ...
Mehdi Jafarpour, Sara Daneshvar, Amir Taher Eftekharsadat, Alireza Khabbazi, Omid Pourbagherian   +4 more
doaj   +1 more source

Multimodality management of soft tissue sarcomas [PDF]

, 1990
Soft tissue sarcomas are a heterogeneous group of malignant tumours arising from connective tissues of mesenchymal origin. By definition sarcomas arising from bone or cartilage are excluded though they have much in common in their behaviour as well as in
Brincat, Stephen
core  

Broadband hyperspectral imaging for breast tumor detection using spectral and spatial information [PDF]

, 2019
Complete tumor removal during breast-conserving surgery remains challenging due to the lack of optimal intraoperative margin assessment techniques. Here, we use hyperspectral imaging for tumor detection in fresh breast tissue.
Dashtbozorg, Behdad, de Boer, Lisanne L., Kho, Esther, Ruers, Theo J. M., Sterenborg, Henricus J. C. M., Van de Vijver, Koen   +5 more
core   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Challenging in leprosy relapse with antiphospholipid syndrome diagnosis: A case report

Clinical Case Reports
Key Clinical Message Infectious diseases like leprosy can cause antiphospholipid antibodies, leading to blood clots. Clinicians should consider this for patients with unusual thrombotic events and prior infectious disease history.
Sousan Kolahi, Leyla Ghadakchi, Amirreza Jabbaripour Sarmadian, Hamideh Azimi, Mehdi Jafarpour, Amirreza Khalaji   +5 more
doaj   +1 more source