Results 51 to 60 of about 391,560 (313)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Ultrasonography features of abdominal perimuscular connective tissue in elite and amateur basketball players: An observational study [PDF]

, 2018
The purpose of this study was to assess and compare with rehabilitative ultrasound imaging (RUSI) the perimuscular connective tissue (PMCT) and interrecti distance (IRD) between elite and amateur basketball players.
Calvo Lobo, César, Buría, José Luis Arias, Romero Morales, Carlos, López, Daniel López, Morales, Carlos Romero, López López, José Manuel, Rodríguez Sanz, David, López-López, Daniel, Polo, Jaime Almazán, González, Sergio Vázquez, Calvo Lobo, César , Vázquez González, Sergio, Almazán Polo, Jaime, Arias Buría, José Luis, Calvo-Lobo, César   +14 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

The influence of type I diabetes mellitus in periodontal disease induced changes of the gingival epithelium and connective tissue

, 2015
Periodontal disease constitutes the most frequent chronic diseases in human dentition. Bacterial plaque is the main etiologic agent, although it is the host immune response that causes periodontal tissue destruction.
Lorencini, M, Reis, JRR, Stach-Machado, DR, Carvalho, HF, Cagnon, VHA, Silva, JAF   +5 more
core   +1 more source

Pregnancy‐associated osteoporosis following in vitro fertilization: A case report

Clinical Case Reports
Key Clinical Message This case report illustrates that in vitro fertilization (IVF) may be a potential risk factor for pregnancy‐associated osteoporosis (PAO), highlighting the need for awareness and monitoring of bone health in women undergoing IVF ...
Mehran Rahimi, Sara Daneshvar, Alireza Khabbazi   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Understanding the Role of Epithelial Cells in the Pathogenesis of Systemic Sclerosis

Cells
Systemic sclerosis (SSc) is an autoimmune fibrotic disorder affecting the skin and internal organs, categorized as either limited cutaneous SSc, where distal areas of skin are involved, or diffuse cutaneous SSc, where more extensive proximal skin ...
Lydia Nagib, Anshul Sheel Kumar, Richard Stratton   +2 more
doaj   +1 more source

Correlation of plasma interleukin-18 concentration and severity of renal involvement and disease activity in systemic lupus erythematosus [PDF]

Journal of Nephropathology, 2016
Background: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by activation of T and polyclonal B lymphocytes. IL-18 was originally identified as a factor which enhances IFN-γ production and is a potent inducer of the ...
Mohammad Reza Jafari-Nakhjavani, Sima Abedi-Azar, Babak Nejati   +2 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source