Results 71 to 80 of about 391,560 (313)

Serum YKL-40 levels and disease characteristics in patients with rheumatoid arthritis

Caspian Journal of Internal Medicine, 2019
Background: The present study aimed to evaluate serum YKL-40 levels in patients with rheumatoid arthritis (RA) compared to healthy subjects and to search whether there is an association between YKL-40 levels and disease characteristics in RA. Methods: In
Mohammad Reza Jafari-Nakhjavani, Amir Ghorbanihaghjo, Babak Bagherzadeh-Nobari, Aida Malek-Mahdavi, Nadereh Rashtchizadeh   +4 more
doaj  

Health-related quality of life impairment is equal for antiphospholipid syndrome whether primary or associated with systemic lupus erythematosus

Rheumatology
Introduction Antiphospholipid syndrome (APS) manifests with thrombosis and pregnancy losses and may significantly impair the health-related quality of life (HRQoL).
Ewa Haladyj, Agata Matusiewicz, Tomasz Wysocki, Marzena Olesinska   +3 more
doaj   +1 more source

Wnt inhibitory factor 1 (WIF1) methylation and its association with clinical prognosis in patients with chondrosarcoma

Scientific Reports, 2017
Chondrosarcoma (CS) is a rare cancer, but it is the second most common primary malignant bone tumor and highly resistant to conventional chemotherapy and radiotherapy.
Pei Liu, Jacson K. Shen, Francis J. Hornicek, Fuyun Liu, Zhenfeng Duan   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Distribution of HLA-DRB1 Alleles in Patients With Antiphospholipid Syndrome and Their Association With Antiphospholipid Antibodies Presence and Damage Indexes

Journal of Immunology Research
Antiphospholipid syndrome (APS) is frequently coexisting with systemic lupus erythematosus (SLE) and the knowledge on its genetic background is essential. The objective of this work was to assess distribution of human leukocyte antigen (HLA)-DRB1 alleles
Ewa Haladyj, Barbara Stypinska, Agata Matusiewicz, Marzena Olesinska, Agnieszka Paradowska-Gorycka   +4 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

High Prevalence of Cold Intolerance in Rheumatoid Arthritis: A Case–Control Study

Clinical Case Reports
Cold intolerance is more common in rheumatoid arthritis patients than control. Cold intolerance tends to develop after rheumatoid arthritis onset and is associated with longer disease duration, with pain and swelling being dominant features.
Mohsen Soroush, Rojin Farzaneh, Elaheh Babapour, Amirreza Jabbaripour Sarmadian, Sami Rassouli, Golrokh Hassanzadeh Behrouz, Amirreza Naseri, Maryam Mahmoudi, Kamal Esalatmanesh, Aida Malek Mahdavi, Alireza Khabbazi   +10 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Fifteen-Year Experience of Pediatric-Onset Mixed Connective Tissue Disease

, 2011
The aim of this study was to investigate the initial clinical manifestations, laboratory data, complications, and outcomes of patients with pediatric-onset mixed connective tissue disease (MCTD) in Taiwan.
俞欣慧;王麗潔;李志鴻;江伯倫, YU, HSIN-HUI;WANG, LI-CHIEH;LEE, JYH-HONG;CHIANG, BOR-LUEN   +1 more
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Análise da biocompatibilidade dos cimentos iRoot SP, MTA FILLAPEX, DiaRoot e MTA BRANCO [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em OdontologiaO objetivo deste estudo foi avaliar a biocompatibilidade dos cimentos iRoot SP, MTA FILLAPEX, DiaRoot e MTA BRANCO ...
Bósio, Claudia Caroline
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