Results 91 to 100 of about 587,613 (311)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Growth/Differentiation Factor 15 Promotes a Pro‐Regenerative Response in Chondrocytes Upon Cartilage Injury

MedComm
Posttraumatic osteoarthritis (PTOA) is a special form of osteoarthritis (OA), developing after joint injuries. Except for some minor clinical differences, no biologic marker has yet been identified to distinguish idiopathic OA (IOA) from PTOA.
Sara Sofi Marques, Alexandra Liebaug, Svenja Maurer, Dietrich Rothenbacher, Rolf E. Brenner, Jana Riegger   +5 more
doaj   +1 more source

Analytical and numerical analyses of the micromechanics of soft fibrous connective tissues

, 2012
State of the art research and treatment of biological tissues require accurate and efficient methods for describing their mechanical properties. Indeed, micromechanics motivated approaches provide a systematic method for elevating relevant data from the ...
A Menzel, AD Freed, AN Gent, D Ambrosi, D Balzani, DE Kiousis, G deBotton, G deBotton, G deBotton, G deBotton, G deBotton, G Shmuel, GA Holzapfel, GA Holzapfel, GA Holzapfel, GA Holzapfel, GA Holzapfel, GA Holzapfel, Gal deBotton, H Chen, I Hariton, I Hariton, J Humphrey, J Stålhand, JD Humphrey, JD Humphrey, JD Humphrey, JD Humphrey, JF Eberth, L Figueiredo Borges de, LA Taber, M Agoras, M Brun, N Gundiah, N Triantafyllidis, NC Avery, O Lopez-Pamies, P Mortier, P Ponte Castañeda, R Hill, RM Nerem, RW Ogden, S Rudykh, Tal Oren, V Alastrué, Y Lanir, YC Fung   +46 more
core   +1 more source

Effect of laser-dimpled titanium surfaces on attachment of epithelial-like cells and fibroblasts. [PDF]

, 2015
PurposeThe objective of this study was to conduct an in vitro comparative evaluation of polished and laserdimpled titanium (Ti) surfaces to determine whether either surface has an advantage in promoting the attachment of epithelial-like cells and ...
Ansari, Sahar, Choi, Seong-Ho, Kim, Jae-Gu, Kim, Meyoung-Kon, Lee, Dong-Woon, Moshaverinia, Alireza, Ryu, Jae-Jun   +6 more
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Drug-Induced Myopathies: A Comprehensive Review and Update

Biomedicines
Drug-induced myopathies are a common cause of muscle pain, and the range of drugs that can cause muscle side effects is constantly expanding. In this article, the authors comprehensively discuss the diagnostic and therapeutic process in patients with ...
Sebastian Miernik, Agata Matusiewicz, Marzena Olesińska   +2 more
doaj   +1 more source

Limited cutaneous systemic sclerosis skin demonstrates distinct molecular subsets separated by a cardiovascular development gene expression signature

Arthritis Research & Therapy, 2017
Background Systemic sclerosis (SSc; scleroderma) is an uncommon autoimmune rheumatic disease characterised by autoimmunity, vasculopathy and fibrosis. Gene expression profiling distinguishes scleroderma from normal skin, and can detect different subsets ...
Emma C. Derrett-Smith, Viktor Martyanov, Cecilia B. Chighizola, Pia Moinzadeh, Corrado Campochiaro, Korsa Khan, Tammara A. Wood, Pier Luigi Meroni, David J. Abraham, Voon H. Ong, Robert Lafyatis, Michael L. Whitfield, Christopher P. Denton   +12 more
doaj   +1 more source

Optimisation of tennis string production from bovine intestine : a thesis presented in partial fulfilment of the requirements for the degree of Master in Technology at Massey University, Palmerston North, New Zealand [PDF]

, 1999
The collagen and elastin content of the beef thread samples ranged from between 47-70% and 1.2-2.5% respectively. Amino acid analysis showed that the collagen present was probably collagen Type I while the non-collagenous proteins predominantly were ...
Komolwattanachai, Kanda
core  

Diamond biocompatible coatings for medical implants [PDF]

, 2016
New carbon (diamond-like) nanocomposite coatings deposited from a C60 ionic beam can be used as a wear-resistant protective coating for implants. It was found that these coatings enhance resistance to тelectrochemical corrosion processes due to a shift ...
Lavrynenko, S. N., Mamalis, A. G., Starikov, V. V., Starikova, S. L.   +3 more
core   +1 more source