Results 81 to 90 of about 391,560 (313)

Molecular Analysis of MEFV Gene Polymorphisms and Mutations in Iranian Azeri Patients with Rheumatoid Arthritis

Iranian Journal of Public Health, 2016
Molecular Analysis of MEFV Gene Polymorphisms and  Mutations in Iranian Azeri Patients with Rheumatoid ...
Alireza KHABBAZI, Farideh ZOLRAHIM, Mehrdad ASGHARI ESTIAR, Ebrahim SAKHINIA, Sousan KOLAHI   +4 more
doaj  

Decreasing Serum Adropin Levels in Patients With Systemic Lupus Erythematosus: A Case‐Control Study

Health Science Reports
Introduction Systematic lupus erythematosus is a complex fundamental autoimmune disease with relapsing‐remitting course and spectrum of disease ranging from mild to life‐threatening illness.
Mehrzad Hajialilo, Amir Ghorbanihaghjo, Kamran Javidi‐Aghdam, Seyed Amir Hossein Seyeddorraji, Alireza Khabbazi, Mehdi Jafarpour   +5 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Connective tissue grafts with nonincised papillae surgical approach for periodontal reconstruction in noncontained defects [PDF]

, 2019
© 2019 Quintessence Publishing Co Inc. This document is the Published, version of a Published Work that appeared in final form in International Journal of Periodontics & Restorative Dentistry .
Ortiz Ruiz, Antonio José, Pecci Lloret, Miguel, Pardo Zamora, Guillermo, Moreno Rodríguez, José Antonio, Caffesse, Raúl G.   +4 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Connective Tissue

In this section of the abdominal wall can be seen collagen, macrophages, and slender fibroblasts within the connective tissue.
Gorski, Roger A.
core   +4 more sources

Growth/Differentiation Factor 15 Promotes a Pro‐Regenerative Response in Chondrocytes Upon Cartilage Injury

MedComm
Posttraumatic osteoarthritis (PTOA) is a special form of osteoarthritis (OA), developing after joint injuries. Except for some minor clinical differences, no biologic marker has yet been identified to distinguish idiopathic OA (IOA) from PTOA.
Sara Sofi Marques, Alexandra Liebaug, Svenja Maurer, Dietrich Rothenbacher, Rolf E. Brenner, Jana Riegger   +5 more
doaj   +1 more source

Drug-Induced Myopathies: A Comprehensive Review and Update

Biomedicines
Drug-induced myopathies are a common cause of muscle pain, and the range of drugs that can cause muscle side effects is constantly expanding. In this article, the authors comprehensively discuss the diagnostic and therapeutic process in patients with ...
Sebastian Miernik, Agata Matusiewicz, Marzena Olesińska   +2 more
doaj   +1 more source