Results 101 to 110 of about 4,769,883 (431)
Cell resolved, multiparticle model of plastic tissue deformations and morphogenesis [PDF]
We propose a three dimensional mechanical model of embryonic tissue dynamics. Mechanically coupled adherent cells are represented as particles interconnected with elastic beams which can exert non-central forces and torques. Tissue plasticity is modeled by a stochastic process consisting of a connectivity change (addition or removal of a single link ...
arxiv +1 more source
Синдром дисплазии соединительной ткани у больных с дилатационной кардиомиопатией [PDF]
Обстежено 90 хворих з дилатаційною кардіоміопатією. Виявлено, що в 24,4 % випадків у хворих діагностуються ознаки синдрому дисплазії сполучної тканини, який у свою чергу, можливо, впливає на перебіг основного захворювання.
Крутиков, Е.С.+3 more
core
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner+7 more
wiley +1 more source
Background Systemic sclerosis (SSc; scleroderma) is an uncommon autoimmune rheumatic disease characterised by autoimmunity, vasculopathy and fibrosis. Gene expression profiling distinguishes scleroderma from normal skin, and can detect different subsets ...
Emma C. Derrett-Smith+12 more
doaj +1 more source
Arthrogryposis: A Rare Manifestation in Infant of Diabetic Mother [PDF]
Arthrogryposis multiplex congenita is characterized by non-progressive, multiple joint contractures present at birth. The major cause of arthrogryposis is fetal akinesia due to fetal abnormalities like neurogenic, muscle, connective tissue abnormalities ...
Kumar, Arvind+2 more
core
Connective Tissue and Fibroblast Senescence in Skin Aging.
M. Wlaschek+3 more
semanticscholar +1 more source
A general Atrophy in scurvy of the connective tissue, and especially of its collagen substance, is proved.
Larry Johnson
semanticscholar +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
An Empirical Bayes Approach for Multiple Tissue eQTL Analysis [PDF]
Expression quantitative trait loci (eQTL) analyses, which identify genetic markers associated with the expression of a gene, are an important tool in the understanding of diseases in human and other populations. While most eQTL studies to date consider the connection between genetic variation and expression in a single tissue, complex, multi-tissue ...
arxiv
ARTIFICIAL ACTIVATION OF THE GROWTH IN VITRO OF CONNECTIVE TISSUE
The experiments have shown that extracts of tissues and tissue juices, under certain conditions, accelerate the growth in intro of the connective tissue from about three to forty times. This activating power was found in many tissues.
A. Carrel
semanticscholar +1 more source