Results 111 to 120 of about 4,769,883 (431)

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

DRUNET: A Dilated-Residual U-Net Deep Learning Network to Digitally Stain Optic Nerve Head Tissues in Optical Coherence Tomography Images [PDF]

open access: yesarXiv, 2018
Given that the neural and connective tissues of the optic nerve head (ONH) exhibit complex morphological changes with the development and progression of glaucoma, their simultaneous isolation from optical coherence tomography (OCT) images may be of great interest for the clinical diagnosis and management of this pathology. A deep learning algorithm was
arxiv  

Structural changes in cartilage and collagen studied by high temperature Raman spectroscopy [PDF]

open access: yes, 2017
Understanding the high temperature behavior of collagen and collagenous tissue is important for surgical procedures and biomaterials processing for the food, pharmaceutical, and cosmetics industries. One primary event for proteins is thermal denaturation
Dudhia, J   +3 more
core   +2 more sources

Diagnosis and treatment of connective tissue disease-associated interstitial lung disease.

open access: yesChest, 2013
Interstitial lung disease (ILD) is one of the most serious pulmonary complications associated with connective tissue diseases (CTDs), resulting in significant morbidity and mortality.
R. Vij, M. Strek
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Роль дисплазії сполучної тканини в розвитку рецидиву генітального пролапсу [PDF]

open access: yes, 2003
В статье приводится анализ данных, посвященных влиянию дисплазии соединительной ткани на развитие рецидива генитального пролапса. За период с 2003 по 2011 год было обследовано и прооперировано 600 гинекологических пациентов с признаками ...
Потапов, В.О.   +4 more
core   +2 more sources

Serum YKL-40 levels and disease characteristics in patients with rheumatoid arthritis

open access: yesCaspian Journal of Internal Medicine, 2019
Background: The present study aimed to evaluate serum YKL-40 levels in patients with rheumatoid arthritis (RA) compared to healthy subjects and to search whether there is an association between YKL-40 levels and disease characteristics in RA. Methods: In
Mohammad Reza Jafari-Nakhjavani   +4 more
doaj  

Distribution of HLA-DRB1 Alleles in Patients With Antiphospholipid Syndrome and Their Association With Antiphospholipid Antibodies Presence and Damage Indexes

open access: yesJournal of Immunology Research
Antiphospholipid syndrome (APS) is frequently coexisting with systemic lupus erythematosus (SLE) and the knowledge on its genetic background is essential. The objective of this work was to assess distribution of human leukocyte antigen (HLA)-DRB1 alleles
Ewa Haladyj   +4 more
doaj   +1 more source

IL-1β Inhibits Human Osteoblast Migration

open access: yesMolecular Medicine, 2013
Bone has a high capacity for self-renewal and repair. Prolonged local secretion of interleukin 1β (IL-1β), however, is known to be associated with severe bone loss and delayed fracture healing.
Nina-Emily Hengartner   +3 more
doaj   +1 more source

In vivo characterization of connective tissue remodeling using infrared photoacoustic spectra [PDF]

open access: yes, 2018
Premature cervical remodeling is a critical precursor of spontaneous preterm birth, and the remodeling process is characterized by an increase in tissue hydration.
Alisio, Mariana   +31 more
core   +1 more source

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