Results 131 to 140 of about 587,613 (311)

Glutathione has cell protective and anti-catabolic effects in articular cartilage without impairing the chondroanabolic phenotype

Heliyon
Joint injuries and consequent oxidative stress is a high-risk factor for developing post-traumatic osteoarthritis (OA). While antioxidative therapy using N-acetylcysteine (NAC) has cell- and chondroprotective effects following cartilage injury, it ...
Svenja Maurer, Michael Fuchs, Rolf E. Brenner, Jana Riegger   +3 more
doaj   +1 more source

Prognostic Value of the Persistence or Change in Pericardial Effusion Status on Serial Echocardiograms in Pulmonary Arterial Hypertension [PDF]

, 2013
Background: Pericardial effusion in pulmonary arterial hypertension (PAH) is an indicator of right heart failure and a marker of poor prognosis; its significance on serial transthoracic echocardiograms (TTE) is not clear.
Dardari, Zeina A.
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Taurine supplementation and systemic lupus erythematosus in preclinical studies: a systematic review of clinical outcomes and underlying mechanisms

Amino Acids
Taurine (Tau) is a sulfur-containing amino acid that has therapeutic roles in several diseases, including inflammatory conditions. The involvement of Tau in modulating systemic lupus erythematosus (SLE) autoimmunity has been indicated in preclinical ...
Aida Malek Mahdavi, Zeinab Javadivala, Niloufar Orooji   +2 more
doaj   +1 more source

Recent developments in connective tissue disease associated pulmonary arterial hypertension

International Journal of Cardiology Congenital Heart Disease
Connective tissue disease associated pulmonary arterial hypertension (CTD-PAH) has benefited from the major treatment advances that have occurred within pulmonary hypertension over the past three decades.
Stefano Rodolfi, Voon H. Ong, Christopher P. Denton   +2 more
doaj   +1 more source

Connective tissue: Get connected with connective tissues [PDF]

The Biochemist, 2003
openaire   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Connective Tissue Proteinpolysaccharides

Journal of Biological Chemistry, 1967
J R Dunstone, M D Frank
openaire   +1 more source

Investigation of diamond biocompatible coatings for medical implants [PDF]

, 2015
Despite the advantages of diamond-like carbon fi lms that are used as wear-resistant coatings for implants, they may have a number of disadvantages such as the high level of internal tension, low adhesive durability and high sensitivity to environment ...
Starikov, V. V., Starikova, S. L.
core