Kaoko O. Kettunen: Skin Arthroplasty in the light of Animal Experiments with special reference to Functional Metaplasia of Connective Tissue [PDF]
, 1959 openalex +1 more source
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
FEBS Open Bio, EarlyView.Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
Age‐Related Changes in Myeloid Cells and Their Impact on Subcutaneous Melanoma Growth in Mice
Aging and Cancer, EarlyView.Our findings reveal that age‐related changes in subcutaneous melanoma growth and immunotherapy response are context‐dependent. In models where tumor growth and treatment resistance increase with age, this effect is partly driven by enhanced immunosuppression from myeloperoxidase‐active Gr‐1⁺ myeloid cells.
Kaitlyn M. Landreth +7 more
wiley +1 more source
Identification and determination of hydroxylysine in connective-tissue proteins [PDF]
, 1969 R.D. Shentall +4 more
openalex +1 more source
The Associations Between Chronic Active Lesions and White Matter Disease: A 7 Tesla Imaging Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background The relationship between paramagnetic rim lesions (PRLs) and surrounding normally appearing white matter (NAWM) disease, potentially contributory to the associations seen between PRLs and clinical impairment, is underexplored. Objectives To assess whether PRLs correlate with a greater degree of NAWM injury in early MS.
Ellie McCluey +17 more
wiley +1 more source
NOTCH2NLC Repeat Expansions in Parkinsonian Disorders: Clinical and Neuroimaging Characteristics
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder caused by NOTCH2NLC GGC repeat expansions, with heterogeneous clinical manifestations, including parkinsonism. Recent studies have identified NOTCH2NLC repeat expansions in patients with Parkinson's disease (PD) and atypical parkinsonism (aPM), suggesting ...
Han‐Lin Chiang +7 more
wiley +1 more source
Unravelling IPAF, VEDOSS and connective tissue diseases classifications through the mixed connective tissue disease spectrum. [PDF]
RMD OpenChevalier K +31 more
europepmc +1 more source
Central Dysmyelination in SSADH‐Deficient Humans and Mice
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer +11 more
wiley +1 more source