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BackgroundRecent evidence has indicated that alterations in energy metabolism play a critical role in the pathogenesis of fibrotic diseases. Studies have suggested that ‘metabolic reprogramming’ involving the glycolysis and oxidative phosphorylation ...
Isabella Gomes Cantanhede+14 more
doaj +1 more source
Role of growth factors in the pathogenesis of tissue fibrosis in systemic sclerosis. [PDF]
The most severe clinical and pathologic manifestations of systemic sclerosis (SSc) are the result of a fibrotic process characterized by the excessive and often progressive deposition of collagen and other connective tissue macromolecules in skin and ...
Castro, Susan V.+2 more
core +2 more sources
Connective tissue anomalies in patients with spontaneous cervical artery dissection. [PDF]
OBJECTIVE: To investigate the prevalence of connective tissue abnormalities in patients with spontaneous cervical artery dissections (sCeAD). METHODS: We systematically assessed clinically detectable signs of connective tissue aberration in a series of ...
A. Giossi+19 more
core +1 more source
Could the super-pulsed CO2 laser be used for oral excisional biopsies? [PDF]
Background. The main purpose of a biopsy is microscopic examination and diagnosis. Keeping the margins of specimens safe and readable is always fundamental to detecting marginal infiltrations or malignant transformation.
Ambrogiano, Simone+6 more
core +1 more source
Connective tissue ulcers [PDF]
Connective tissue disorders (CTD), which are often also termed collagen vascular diseases, include a number of related inflammatory conditions. Some of these diseases include rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis (scleroderma), localized scleroderma (morphea variants localized to the skin), Sjogren's syndrome ...
Ganary Dabiri+2 more
openaire +3 more sources
A genome-wide association study identifies four novel susceptibility loci underlying inguinal hernia. [PDF]
Inguinal hernia repair is one of the most commonly performed operations in the world, yet little is known about the genetic mechanisms that predispose individuals to develop inguinal hernias.
Ahituv, Nadav+8 more
core +2 more sources
Host reaction in paratenic fish hosts against 3rd stage larvae of Anguillicola crassus [PDF]
Many fish species of Lake Balaton (Hungary) serve as paratenic hosts for the 3rd stage larvae of the eel parasite Anguillicola crassus. The incidence oi different phases of the host reaction varies with paratenic fish host but its nature is basically the
Molnár, Kálmán+2 more
core +1 more source
The connective tissue index of Helix aspersa as a metal biomarker [PDF]
Copyright © 2004, Springer Netherlands.The digestive gland of adult land snails, Helix aspersa, sampled from four different sites in São Miguel island (Azores) was submitted to chemical analyses, autometallography and haemalum/eosin staining, in order to
Amaral, André+3 more
core +1 more source
Programmed biomolecule delivery to enable and direct cell migration for connective tissue repair
Dense connective tissue injuries have limited repair, due to the paucity of cells at the wound site. We hypothesize that decreasing the density of the local extracellular matrix (ECM) in conjunction with releasing chemoattractive signals increases ...
Feini Qu+4 more
semanticscholar +1 more source
A lumpy back: extensive cutaneous collagenomas [PDF]
A widespread form of eruptive collagenomas in a 12-year-old man is presented for the impressive iconography, challenging differential diagnosis, and histopathological considerations associated with such rare connective tissue disorders.
Agosta, Daniele+4 more
core +2 more sources