Multi‐omics profiling reveals key factors involved in Ewing sarcoma metastasis
Molecular Oncology, Volume 19, Issue 4, Page 1002-1028, April 2025.Using a mouse model that recapitulates the spread of tumor cells within the body, we have profiled paired tumors and metastasis samples using a multiomics approach combining different layers of biological information. We identified key genes that drive metastasis in Ewing sarcoma.
Mariona Chicón‐Bosch +11 more
wiley +1 more source
"Mixed connective tissue disease": a condition in search of an identity [PDF]
, 2020 Mixed connective tissue disease was first described as a new autoimmune rheumatic disease in 1972 based on the claim of a distinct clinical picture associated with anti-RNP antibody positivity.
Alves, MR, Isenberg, DA
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Hereditary Connective Tissue Diseases and Risk of Post-Acute SARS-CoV-2
VirusesWe completed a retrospective review of data collected by the JH-CROWN consortium based on ICD10 codes for a hospitalized cohort. The severity and prevalence of COVID-19 and development of PASC within heritable connective tissue diseases were unknown ...
Maggie L. Bartlett +2 more
doaj +1 more source
Association of anti-phospholipid antibodies with connective tissue diseases
Indian Dermatology Online Journal, 2015 Background: The antiphospholipid antibodies (APLA) are directed against phospholipids and their binding proteins and are frequently found in association with connective tissue disorders. Systemic lupus erythematoses (SLE) with APLA may cause a diagnostic
Reena Rai, T Swetha
doaj +1 more source
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, EarlyView.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source
Cardiac valvular disease in chronic inflammatory disorders of connective tissue. Factors influencing survival after surgery. [PDF]
, 1975 D B Yates, J. T. Scott
openalex +1 more source
Rituximab compared to intravenous cyclophosphamide in adults with connective tissue disease-associated interstitial lung disease: the RECITAL RCT [PDF]
BACKGROUND: Interstitial lung disease frequently complicates systemic autoimmune disorders including scleroderma, idiopathic inflammatory myositis and mixed connective tissue disease, resulting in considerable morbidity and mortality.
Ashby, Deborah +17 more
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Molecular Oncology, Volume 19, Issue 5, Page 1299-1309, May 2025.Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen +6 more
wiley +1 more source
The arthritis of mixed connective tissue disease. [PDF]
, 1978 Robert M. Bennett, Denis J. O'Connell
openalex +1 more source
Evolution of undifferentiated connective tissue disease [PDF]
Introduction. Undifferentiated connective tissue disease (UCTD) is characterized by symptoms of autoimmune disease that do not meet the criteria for any specific connective tissue disease (CTD).
Mustapha, Asghiri
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