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Mixed connective tissue disease
Best Practice & Research Clinical Rheumatology, 2016The concept of mixed connective tissue disease (MCTD) as a separate connective tissue disease (CTD) has persisted for more than four decades. High titers of antibodies targeting the U1 small nuclear ribonucleoprotein particle (U1 snRNP) in peripheral blood are a sine qua non for the diagnosis of MCTD, in addition to distinct clinical features including
Ragnar, Gunnarsson +3 more
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Clinics in Plastic Surgery, 1993
The classic connective tissue diseases (lupus erythematosus, dermatomyositis, and scleroderma) have been described with respect to their pathogenesis, clinical picture, laboratory diagnosis, and management. Because the aim of this volume is to provide an interface between plastic surgery and dermatology, the cutaneous manifestations, both shared and ...
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The classic connective tissue diseases (lupus erythematosus, dermatomyositis, and scleroderma) have been described with respect to their pathogenesis, clinical picture, laboratory diagnosis, and management. Because the aim of this volume is to provide an interface between plastic surgery and dermatology, the cutaneous manifestations, both shared and ...
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Autoimmune connective tissue diseases
Best Practice & Research Clinical Obstetrics & Gynaecology, 2015Rheumatic diseases (RDs) occur preferentially in women, often during the childbearing age. The interaction of pregnancy and the RD is varied, ranging from spontaneous improvement to aggravation of disease symptoms or life-threatening flares. Risks for the mother with RD and the child differ in regard to the presence of organ manifestations, organ ...
M. Østensen, I. Cetin
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Connective Tissue Disease–related Thoracic Disease
Clinics in Chest Medicine, 2015Pulmonary involvement is a frequent manifestation of connective tissue disease (CTD)-related thoracic disease. It is important to characterize the underlying pattern when pulmonary involvement occurs in a patient with CTD, and to exclude other causes.
Yutaka, Tsuchiya +3 more
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Mixed connective tissue disease
Lupus, 2006Mixed connective tissue disease (MCTD) was first described in 1972 as a disease syndrome with overlapping features of systemic sclerosis, systemic lupus erythematosus (SLE) and polymyositis associated with antibodies to RNAse sensitive extractable nuclear antigen.
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Connective Tissue Disease–Associated Lung Disease
Immunology and Allergy Clinics of North America, 2012This article provides a broad overview of the complex intersection between the connective tissue diseases (CTDs) and their pulmonary manifestations. Indirect pulmonary complications - such as respiratory infection and medication-induced lung toxicity - are briefly discussed, and the importance of a comprehensive assessment of the patient with CTD with ...
Amy L, Olson +2 more
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Mixed Connective Tissue Disease
2008Mixed connective tissue disease (MCTD) is a condition characterized by the overlap of features of systemic lupus erythematosus (SLE), systemic sclerosis (SSc) and polydermatomyositis (PM/DM) in association with high titers of antibodies against a ribonuclear protein (RNP).
MOSCA, MARTA +2 more
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Mixed Connective Tissue Disease
Radiologic Clinics of North America, 1988MCTD is characterized by clinical features that overlap those of several of the classic rheumatic and connective tissue disorders. Although MCTD has been distinguished from them by the presence of antibodies to an RNP and by specific immunoregulatory T cell circuit abnormalities, its definitive placement among the classic disorders remains ...
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Pleural Diseases in Connective Tissue Diseases
Seminars in Respiratory and Critical Care MedicineAbstractConnective tissue diseases (CTD) are heterogeneous, immune-mediated inflammatory disorders often presenting with multiorgan involvement. With the advent of high-resolution computed tomography, CTD-related pleuritis—pleural thickening and effusion—is now increasingly recognized early in the disease trajectory.
Hui, Guo +2 more
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