Results 61 to 70 of about 542,433 (374)

Microglial memory of early life stress and inflammation: susceptibility to neurodegeneration in adulthood [PDF]

Neurosci Biohav Rev 2019, 2019
We review evidence supporting the role of early life programming in the susceptibility for adult neurodegenerative diseases while highlighting questions and proposing avenues for future research to advance our understanding of this fundamental process.
arxiv   +1 more source

Vasculitis associated with psoriatic arthritis: a case report

Egyptian Rheumatology and Rehabilitation
Background Psoriatic arthritis is a chronic inflammatory condition associated with psoriasis, which affects joints. The coexistence of vasculitis, an inflammation of blood vessels, with psoriatic arthritis is rare, highlighting a complex interplay ...
Mehdi Jafarpour, Bita Rahbari, Bahareh Mehramuz, Sara Daneshvar   +3 more
doaj   +1 more source

Assessment of education requirements for patients with rheumatoid arthritis, based on the Polish version of the Educational Needs Assessment Tool (Pol-ENAT), in the light of some health problems – A cross-sectional study

Annals of Agricultural and Environmental Medicine, 2016
Introduction Patients with chronic rheumatoid arthritis (RA) need advice in order to face the problems of everyday life, as well as suffering associated with the disease.
Matylda Sierakowska, Małgorzata Klepacka, Stanisław Józef Sierakowski, Katarzyna Pawlak-Buś, Piotr Leszczyński, Maria Majdan, Marzena Olesińska, Wojciech Romanowski, Małgorzata Bykowska-Sochacka, Sławomir Jeka, Justyna Anna Sierakowska, Mwidimi Ndosi, Elżbieta Krajewska-Kułak   +12 more
doaj   +1 more source

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

FEBS Letters, Volume 599, Issue 7, Page 927-951, April 2025.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine, Matteo Mucci, Antonio Recchiuti, Domenico Mattoscio   +3 more
wiley   +1 more source

Spotlight on nerves: Portable multispectral optoacoustic imaging of peripheral nerve vascularization and morphology [PDF]

arXiv, 2022
Various morphological and functional parameters of peripheral nerves and their vascular supply are indicative of pathological changes due to injury or disease. Based on recent improvements in optoacoustic image quality, we explore the ability of multispectral optoacoustic tomography, in tandem with ultrasound imaging (OPUS), to investigate the vascular
arxiv  

Sjogren's syndrome: An underdiagnosed condition in mixed connective tissue disease [PDF]

, 2014
OBJECTIVE: To determine the prevalence of sicca symptoms, dry eye, and secondary Sjögren's syndrome and to evaluate the severity of dry eye in patients with mixed connective tissue disease.
Alves, Milton Ruiz, Caleiro, Maria Teresa C., Fuller, Ricardo, Lopes, Jaqueline Barros, Pasoto, Sandra Gofinet, Usuba, Fany Solange, Yamamoto, Joyce Hisae   +6 more
core   +3 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Rituximab in autoimmune connective tissue disease-associated interstitial lung disease [PDF]

, 2016
Objective. CTD-associated interstitial lung disease (ILD) often fails to respond to conventional immunomodulatory agents. There is now considerable interest in the use of rituximab in systemic autoimmune CTD in patients refractory to standard treatments.
Adamali, Huzaifa, Dodds, Nick, Edey, Anthony, Gunawardena, Harsha, Mayers, Lloyd, McCabe, Melanie, Millar, Ann B, Sharp, Charles   +7 more
core   +1 more source

The Possible Relation of Demodex and Facial Erythema in Connective Tissue Diseases

Iranian Journal of Parasitology, 2023
Background: We aimed to investigate the frequency of Demodex infestation and clinical implications in connective tissue disease patients with facial erythema.
Abdulsamet Erden, Berkan Armağan, Serdar Can Güven, Özlem Karakaş, Fatma Erden, Bahar Özdemir, Ahmet Omma, Orhan Küçükşahin   +7 more
doaj   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source