Results 51 to 60 of about 1,199,246 (381)

Correlation of plasma interleukin-18 concentration and severity of renal involvement and disease activity in systemic lupus erythematosus [PDF]

Journal of Nephropathology, 2016
Background: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by activation of T and polyclonal B lymphocytes. IL-18 was originally identified as a factor which enhances IFN-γ production and is a potent inducer of the ...
Mohammad Reza Jafari-Nakhjavani, Sima Abedi-Azar, Babak Nejati   +2 more
doaj   +1 more source

Clinical Features of Neuropsychiatric Syndromes in Systemic Lupus Erythematosus and Other Connective Tissue Diseases

Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders, 2016
Systemic lupus erythematosus (SLE) and related disorders are chronic inflammatory diseases characterized by abnormalities and, in some cases, even complete failure of immune responses as the underlying pathology.
T. Kasama, A. Maeoka, N. Oguro
semanticscholar   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Ocular involvement in rheumatic diseases

Rheumatology, 2023
Rheumatic diseases are associated with a significant decline in quality of life, which is not only related to the progression of the underlying disease but also to the development of coexisting conditions.
Iwona Dankiewicz- Fares, Daniel Jeka, Tacjana Barczyńska   +2 more
doaj   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Dentz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source

Spectrum of Large and Medium Vessel Vasculitis in Adults: Primary Vasculitides, Arthritides, Connective Tissue, and Fibroinflammatory Diseases [PDF]

, 2022
Luca Seitz, Pascal Seitz, Roxana Pop, Fabian Lötscher   +3 more
openalex   +1 more source

Ultra‐rare sarcomas: A consensus paper from the Connective Tissue Oncology Society community of experts on the incidence threshold and the list of entities

Cancer, 2021
Among sarcomas, which are rare cancers, many types are exceedingly rare; however, a definition of ultra‐rare cancers has not been established. The problem of ultra‐rare sarcomas is particularly relevant because they represent unique diseases, and their ...
S. Stacchiotti, A. Frezza, J. Blay, E. Baldini, S. Bonvalot, J. Bovée, D. Callegaro, P. Casali, R. Chiang, G. Demetri, Elizabeth G. Demicco, J. Desai, M. Eriksson, H. Gelderblom, S. George, M. Gounder, A. Gronchi, Abha A. Gupta, R. Haas, Andrea Hayes-Jardon, P. Hohenberger, Kevin B. Jones, Robin L. Jones, B. Kasper, A. Kawai, D. Kirsch, E. Kleinerman, A. Le Cesne, Jiwon Lim, M. C. Chirlaque López, R. Maestro, R. Marcos-Gragera, Javier Martin Broto, T. Matsuda, O. Mir, Shreyaskumar R Patel, C. Raut, A. Razak, D. Reed, P. Rutkowski, R. Sanfilippo, M. Sbaraglia, I. Schaefer, D. Strauss, K. Sundby Hall, W. Tap, David M. Thomas, W. V. D. van der Graaf, W. V. van Houdt, O. Visser, M. von Mehren, A. Wagner, Breelyn A. Wilky, Y. Won, C. Fletcher, A. D. Dei Tos, A. Trama   +56 more
semanticscholar   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Роль дисплазії сполучної тканини в розвитку рецидиву генітального пролапсу [PDF]

, 2003
В статье приводится анализ данных, посвященных влиянию дисплазии соединительной ткани на развитие рецидива генитального пролапса. За период с 2003 по 2011 год было обследовано и прооперировано 600 гинекологических пациентов с признаками ...
Потапов, В.О., Банахевич, Р.М., Золотарьов, Д.Л., Акимова, К.Б., Єчин, А.В.   +4 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source