Results 61 to 70 of about 3,936,691 (310)

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Pregnancy‐associated osteoporosis following in vitro fertilization: A case report

Clinical Case Reports
Key Clinical Message This case report illustrates that in vitro fertilization (IVF) may be a potential risk factor for pregnancy‐associated osteoporosis (PAO), highlighting the need for awareness and monitoring of bone health in women undergoing IVF ...
Mehran Rahimi, Sara Daneshvar, Alireza Khabbazi   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Original paper Assessment of the level of vaccine-induced anti-HBs antibodies in children with inflammatory systemic connective tissue diseases treated with immunosuppression

, 2015
Objectives : Protective vaccinations are the most effective method of prevention of type B virus hepatitis. The aim of the study was to determine whether in children receiving immunosuppressive therapy due to inflammatory systemic connective tissue ...
Małgorzata Kwiatkowska, Elżbieta Hernik, Agnieszka Gazda, Beata Kołodziejczyk, Izabela Szczygielska, Lidia Rutkowska-Sak   +5 more
core   +1 more source

Understanding the Role of Epithelial Cells in the Pathogenesis of Systemic Sclerosis

Cells
Systemic sclerosis (SSc) is an autoimmune fibrotic disorder affecting the skin and internal organs, categorized as either limited cutaneous SSc, where distal areas of skin are involved, or diffuse cutaneous SSc, where more extensive proximal skin ...
Lydia Nagib, Anshul Sheel Kumar, Richard Stratton   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Subepithelial connective tissue grafts (SCTGS) in periodontology

, 2020
Periodontal plastic surgery applications have increased in modern dentistry as the importance of patients to their appearance. For this purpose, many techniques and flap designs have been used to treat gingival recession, but subepithelial connective ...
Karakan N.C., Alpan A.L.
core  

A clinical study of connective tissue diseases

, 2015
Background: Connective tissue diseases are defined as a group of auto-immune disorders that have in common, immunological and inflammatory changes in blood vessels and connective tissues.
Sandeep Kodali, M Lavanya, L V N.Reddy, Kotha Sravanthi, N Nagendra Chary   +4 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

The expression and methylation status of vitamin D receptor gene in Behcet's disease

Immunity, Inflammation and Disease, 2019
Introduction Vitamin D has important roles as a natural immune modulator via regulating the expression of genes which have been implicated in the pathophysiology of autoimmune diseases.
Sam Seydi Shirvani, Mohammad Nouri, Ebrahim Sakhinia, Zohreh Babaloo, Golamreza jadideslam, Alipour Shahriar, Jafar Farhadi, Alireza khabbazi   +7 more
doaj   +1 more source