Results 51 to 60 of about 3,936,691 (310)
Clinical Case Reports, 2023 Key Clinical Message Castleman disease is an infrequent disease that affects the lymph nodes and related tissues. The condition may manifest with lymphadenopathy, characterized by the enlargement of the lymph nodes, alongside additional symptoms such as ...
Alireza Khabbazi +4 more
doaj +1 more source
eLife, 2023 Accumulation of dysfunctional chondrocytes has detrimental consequences on the cartilage homeostasis and is thus thought to play a crucial role during the pathogenesis of osteoarthritis (OA).
Jana Riegger, Rolf E Brenner
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The real connective tissue diseases [PDF]
Clinical Medicine, 2001 L'A. decrit les syndromes pathologiques lies aux pathologies des tissus conjonctifs, particulierement les tissus musculaires et ...
Wordsworth, P, Halliday, D
openaire +3 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Nontyphoidal Salmonella bacteremia in patients with connective tissue diseases
, 2012 [[abstract]]Background/Purpose: Nontyphoidal Salmonella (NTS) is a crucial pathogen in immunocompromised patients, especially those with connective tissue disease (CTD) and corticosteroid or immunosuppressant therapy. The aim of this study is to identify
Huang, CF;Chen, PL;Liu, MF;Lee, CC;Lee, NY;Chang, CM;Lee, HC;Wu, CJ;Ko, WC
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Vitamin D and connective tissue diseases
, 2020 Objective and design: Recently, many studies have shown that the biologically active form of vitamin D—1,25(OH)2 D—is involved in many biological processes, including immune system modulation, and patients affected by various autoimmune diseases, such as
Cantatore F. P. +3 more
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Correlation of plasma interleukin-18 concentration and severity of renal involvement and disease activity in systemic lupus erythematosus [PDF]
Journal of Nephropathology, 2016 Background: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by activation of T and polyclonal B lymphocytes. IL-18 was originally identified as a factor which enhances IFN-γ production and is a potent inducer of the ...
Mohammad Reza Jafari-Nakhjavani +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source