Results 91 to 100 of about 216,496 (307)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Experimental study on AR fiberglass connectors for bridges made of composite materials
Materiales de Construccion, 2006 One highly relevant aspect in composite material bridgedesing is the study of the shear connectors to be used.Composite material bridges most commonly comprise acomposite deck resting on steel or reinforced concrete girders.This article analyzes the ...
A. Miravete +7 more
doaj +1 more source
Connection space reduction mechanism [PDF]
, 1992 A connector assembly comprised of two halves, each respectively including a shell type connector subassembly, one being an active half and the other being a passive half is described.
Milam, Malcolm Bruce
core +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
An MT-Style Optical Package for Optical Data Transmission
, 2003 An optical package for mounting VCSEL and PIN diodes for transmitting and receiving optical signals has been developed. The diodes couple to the fibers in a commercial MT connector.
Dinkespiler, K.K Gan
core +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Current Study on Choke and Kill Line Connector of Subsea BOP Stack
Shiyou jixie, 2016 Choke and kill line connector is the key equipment of subsea blowout preventer stack,of which the core technology is mainly controlled by a few foreign BOP manufacturers.To guarantee our country’s energy security and protect our maritime rights and ...
Hou Guoqing
doaj
Design and application of a general connector for drainage tube (一种引流管通用连接器的设计与应用)
中西医结合护理Peritoneal irrigation and drainage plays an important role in abdominal surgery. Peritoneal infection, effusion and hematoma may prolong hospital stay and increase the consumption of medical resources.
FAN Chunmei (范春梅) +1 more
doaj +1 more source
Electrical self-aligning connector [PDF]
, 1983 A self-aligning electrical connector device includes a receptacle component having a conically contoured interior and a plug component having a correspondingly contoured conical body receivable in the receptacle component. The plug component has a number
Clark, K. H., Scott, D. R.
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source