Results 111 to 120 of about 269,529 (357)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Pocket gauge for checking insert clocking of multipin circular connectors [PDF]

open access: yes, 1974
Prototype gauge has been constructed of heavy clear plastic with engraved degree lines, numerals, and alignment lines. With suitable modification, gauge can be mass produced. It could be marketed directly to users or to manufacturers of circular multipin
Billmeyer, E.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Flexible electrical conductors for high-temperature switchgear [PDF]

open access: yes, 1970
Arch-shaped conductors fabricated from flat strips of beryllium oxide dispersion-strengthened copper alloy serve as flexible electrical connectors capable of operating in 1000 deg F temperature range, under vacuum conditions for periods of 10,000 hours ...
Koutnik, E. A.   +2 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Electrodeposited Silver Alloys: Screening of Alloying Elements and Related Properties and Applications

open access: yesECS Advances
Electrodeposited silver alloys are gaining prominence as high-performance alternatives to pure silver coatings, driven by the demand for durable connectors and cost-effective catalysts, as well as by environmental and regulatory pressures to replace ...
Q. Orecchioni   +3 more
doaj   +1 more source

Three-Dimensional Finite-Element Analysis of the Short-Time and Peak Withstand Current Tests in Substation Connectors

open access: yesEnergies, 2016
Power devices intended for high-voltage systems must be tested according to international standards, which includes the short-time withstand current test and peak withstand current test.
Francesca Capelli   +2 more
doaj   +1 more source

Connector theory [PDF]

open access: yesPacific Journal of Mathematics, 1975
Nakano, Hidegoro, Nakano, Kazumi
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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