Results 101 to 110 of about 60,587 (295)
Scenario-based software architecture for designing connectors framework in distributed system [PDF]
, 2011 Software connectors is one of key word in enterprise information system. In recent years, software developers have facing more challenges of connectors which are used to connect distributed components.
Mcheick, Hamid, Mili, Hafedh, Qi, Yan
core
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Automated Synthesis of CONNECTors to support Software Evolution [PDF]
, 2012 http://ercim-news.ercim.eu/en88/Today's software systems are increasingly networked and are further characterized by ever-changing functionalities provided to/required from the networked environment because of the wide variety of dynamically available ...
Inverardi, Paola +3 more
core
, 2014 Connector proteins that were found to be strong inter-connectors by OverMod when applied to: (i) all three hard partitions, (ii) two out of three hard partitions (italics).Robust inter-connectors.
Laura Bennett (430535) +4 more
core +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Architecture, Civil Engineering, EnvironmentThe article presents the results of original research on wall connections made of autoclaved aerated concrete subjected to shear with bending. The shape of the test element and the test stand layout were innovatively selected based on the author’s ...
GALMAN Iwona +3 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
A Formalization of Mediating Connectors: Towards on the fly Interoperability
, 2009 Mediators stand as a core architectural paradigm for today's and future systems that increasingly need be connected. The mediator concept has been used to cope with many heterogeneity dimensions spanning: terminology, representation format, transfer ...
Inverardi, Paola +2 more
core
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source