Results 81 to 90 of about 55,399 (296)

Acquisition of Variation in the Use of alors, donc, fait que by Advanced French-as-a-Second-Language Learners in Ontario, Canada

Languages
This study examines the acquisition of sociolinguistic variation in the use of French connectors alors/donc/fait que ‘so’ by two groups of advanced French-as-a-second language (FL2) learners in Ontario: (i) high school French Immersion (FI) students and (
Françoise Mougeon, Raymond Mougeon, Katherine Rehner   +2 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Executable Connectors: Towards Reusable Design Elements [PDF]

, 1997
. The decomposition of a software application into components and connectors at the design stage has been promoted as a way to describe and reason about complex software architectures.
Tamar Richner, Ducasse, Stephane, Stéphane Ducasse, Richner, Tamar   +3 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Fretting corrosion and the reliability of multicontact connector terminals [PDF]

, 2002
The harsh operating environment of the automotive application makes the semi-permanent connector susceptible to intermittent high contact resistance which eventually leads to failure. Fretting corrosion is often the cause of these failures.
Swingler, Jonathan, McBride, John W., Swingler, J., McBride, J.W.   +3 more
core   +1 more source

Grammar. Linguistics. Language (in response to opposing views)

Слово.ру: балтийский акцент
I discuss the criteria of defining linguistics against other science branches. Lin­guistics is not a proper part of semiotics, since the foundations of language do not necessarily rely on the theory of sign systems.
Anton V. Zimmerling
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Research and developments on strength and durability prediction of composite beams utilising bolted shear connectors (review)

, 2020
The use of bolted shear connectors in both new construction and for strengthening damaged and substandard infrastructures has become an attractive option to increase the load-carrying capacity or fatigue strength of a design.
Mirza, Olivia (R13978), Hosseini, Seyedeh M. (S33738), Mashiri, Fidelis R. (R12397)   +2 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source