Results 81 to 90 of about 60,587 (295)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Electrodeposited Silver Alloys: Screening of Alloying Elements and Related Properties and Applications

open access: yesECS Advances
Electrodeposited silver alloys are gaining prominence as high-performance alternatives to pure silver coatings, driven by the demand for durable connectors and cost-effective catalysts, as well as by environmental and regulatory pressures to replace ...
Q. Orecchioni   +3 more
doaj   +1 more source

Les connecteurs, de la grammaire à la littéracie

open access: yesLidil, 2017
The evaluations of the skills of the learners in French constitute revelations of their difficulties, in particular in their knowledge of the language and in four skills.
Sabina Mahmudova
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

A study of connectors in English texts written by Italian and German students

open access: yes, 2022
openCorpus linguistics is the study of languages with an empirical approach consisting in the analysis of written or oral texts, collected with specific characteristics depending on the purpose of the research.
FLORIS, MARIA ELISABETTA
core  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Analysis of an alternative topology for steel-concrete-steel sandwich beams incorporating inclined shear connectors

open access: yes, 2011
This thesis presents a new concept in steel-concrete-steel sandwich construction in which a bi-directional corrugated-strip core is proposed as an alternative inclined shear connector.
Leekitwattana, M., Leekitwattana, Manit
core   +1 more source

An Algorithm for Packing Connectors

open access: yesJournal of Combinatorial Theory, Series B, 1998
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +6 more sources

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

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