Results 61 to 70 of about 269,529 (357)

Process description of SWQN : A simplified hydraulic model [PDF]

open access: yes, 2009
SWQN is a simplified hydraulic model for surface water systems which computes water levels and flows in a network of nodes labelled as ‘volumes’ and segments labelled as ‘connectors’.
Gerven, L.P.A., van   +2 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Specifying Software Connectors [PDF]

open access: yes, 2005
Orchestrating software components, often from independent suppliers, became a central concern in software construction. Actually, as relevant as components themselves, are the ways in which they can be put together to interact and cooperate in order to achieve some common goal.
Marco Antonio Barbosa   +1 more
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Treo: Textual Syntax for Reo Connectors [PDF]

open access: yes, 2018
Reo is an interaction-centric model of concurrency for compositional specification of communication and coordination protocols. Formal verification tools exist to ensure correctness and compliance of protocols specified in Reo, which can readily be (re ...
Arbab, Farhad, Dokter, Kasper
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Heritage and Social Prescribing - Historic England's learnings from pilots and collaborative work across sectors 2023-2024

open access: yesInternet Archaeology
The last five years have seen an increased awareness and growing evidence about the potential of social prescribing to help address health inequalities and help take some of the pressures off the National Health Service (NHS). Consequently, more and more
Desi Gradinarova
doaj   +1 more source

RF shielded connectors [PDF]

open access: yes, 1974
Gap, where cable joins connector housing, is shielded effectively by composite RF shielding made from suitable potting resin material (fumed silica, thixotropic prepolymer composition), conductive coating (silver-filled, flexible, polyurethane resin ...
Clatterbuck, C., Fisher, A.
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy