Results 181 to 190 of about 64,299 (311)

Calhm6 Governs Macrophage Polarization Through Chp1‐Camk4‐Creb1 Axis and Ectosomal Delivery in Inflammatory Responses

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin   +14 more
wiley   +1 more source

Connexins in Acquired Hearing Loss: Expanding Research Perspectives. [PDF]

open access: yesBiomedicines
Huang S   +7 more
europepmc   +1 more source

Reviewer #2 (Public review): CO2-dependent opening of Connexin 43 hemichannels

open access: gold
Valentin-Mihai Dospinescu   +7 more
openalex   +1 more source

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

open access: yesAdvanced Science, Volume 13, Issue 3, 14 January 2026.
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin   +3 more
wiley   +1 more source

Connexins and Aging-Associated Respiratory Disorders: The Role in Intercellular Communications

open access: green
T.V. Zubareva   +7 more
openalex   +2 more sources

Correction: Connexin 43 inhibitors reduce cell viability in glioblastoma and astrocyte co-culture systems [PDF]

open access: bronze
Ali Genc   +5 more
openalex   +1 more source

Mapping Satellite Glial Cell Heterogeneity Reveals Distinct Spatial Organization and Implies Functional Diversity in the Dorsal Root Ganglion

open access: yesAdvanced Science, Volume 13, Issue 1, 5 January 2026.
Four distinct satellite glial cell subtypes are identified in mouse dorsal root ganglia using single‐cell RNA sequencing and spatial validation. These subtypes show unique marker profiles and anatomical distributions. Human dorsal root ganglia display layered perisomatic organization with differential marker expression.
Ole Andreas Ahlgreen   +13 more
wiley   +1 more source

Mitochondrial Adaptation to Mechanical Stress in Cardiac Ageing and Disease

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
Mechanical forces shape the heart's energy factories. This review explores how mitochondria in cardiac cells sense and respond to biomechanical stress, altering their structure, positioning, and metabolism. By linking mechanical cues to mitochondrial adaptation, the article highlights pathways driving heart disease and points to new strategies for ...
Aishwarya Prakash, Thomas Iskratsch
wiley   +1 more source

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