Results 161 to 170 of about 56,231 (274)

Astrocytes as central integrators of neural circuit function: Mechanisms and dysregulation in neuropsychiatric disorders

open access: yesClinical and Translational Discovery, Volume 6, Issue 2, April 2026.
1. Astrocytes are central integrators of neural circuit function through tripartite synapse modulation and neurovascular coupling. 2. Dysregulation of glutamate/GABA homeostasis and neuroinflammation represents shared mechanisms across diverse neuropsychiatric disorders. 3.
Xinyu Liu   +10 more
wiley   +1 more source

The Metabolic Role of Mitochondria in the Perinatal Cardiac Development and Cardiovascular Diseases

open access: yesExploration, Volume 6, Issue 2, April 2026.
This review explores the critical role of mitochondria in heart development and cardiovascular disease. It highlights how mitochondrial maturation during embryonic‐to‐postnatal transition, regulated by oxygen and metabolic changes, shapes cardiac structure and function.
Minghao Li   +3 more
wiley   +1 more source

Effects of Diet Strategy and Nutrients on the Progression and Prevention of Diabetic Cardiomyopathy: A Narrative Review

open access: yesFood Science &Nutrition, Volume 14, Issue 4, April 2026.
Dietary strategies modulate the progression of diabetic cardiomyopathy by targeting oxidative stress, inflammation, mitochondrial dysfunction, and myocardial fibrosis. Specific nutrients and bioactive compounds, as well as caloric restriction, improve myocardial metabolism and redox balance, whereas ketogenic diets exert time‐dependent beneficial or ...
Wen‐hui Deng   +9 more
wiley   +1 more source

Editorial: Pannexin and connexin signaling in cell death and tissue health and disease

open access: yesFrontiers in Cell and Developmental Biology, 2023
Marc Mesnil   +2 more
doaj   +1 more source

Dysferlin stabilizes membrane nanodomains of cardiomyocytes after myocardial infarction. [PDF]

open access: yesSci Rep
Wegener JB   +19 more
europepmc   +1 more source

Pharmacological Separation of Mechanosensory Mechanisms in Rat Urinary Bladder Ex Vivo

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
ABSTRACT The local response of the bladder wall to stretch is believed to result from the coordinated activation of mechanosensitive ion channels located in the plasma membrane of the cells that form the wall's urothelial and detrusor smooth muscle (DSM) layers.
Igor B. Philyppov   +4 more
wiley   +1 more source

Toxicological evaluation of paracetamol and ibuprofen: genetic and hematological alterations in male albino mice. [PDF]

open access: yesBMC Pharmacol Toxicol
Elgingihy SM   +5 more
europepmc   +1 more source

pH‐Dependent Microenvironmental Ionic Signaling in Pancreatic Ductal Adenocarcinoma

open access: yesActa Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim Pancreatic ductal adenocarcinoma (PDAC) develops within a uniquely dynamic pH landscape shaped by substantial acid–base fluxes produced by the exocrine pancreas. Secretion of alkaline pancreatic juice, normally linked to digestion, produces intermittent acidifications of the pancreatic interstitium, which challenges epithelial and stromal ...
Albrecht Schwab   +37 more
wiley   +1 more source

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