Molecular Modeling and Dynamics of a Complete Connexin-43 Gap Junction Channel in Various Phosphorylation States. [PDF]
Gao Y, Zuo J, Falk MM, Im W.
europepmc +1 more source
1. Astrocytes are central integrators of neural circuit function through tripartite synapse modulation and neurovascular coupling. 2. Dysregulation of glutamate/GABA homeostasis and neuroinflammation represents shared mechanisms across diverse neuropsychiatric disorders. 3.
Xinyu Liu +10 more
wiley +1 more source
Differences of immunohistochemical profiling of MOC-31, caveolin-1, connexin-43, Ki-67 in ameloblastic fibroma, ameloblastic fibrodentinoma, ameloblastic fibro-odontoma, and odontomas. [PDF]
Umpiérrez NG +4 more
europepmc +1 more source
The Metabolic Role of Mitochondria in the Perinatal Cardiac Development and Cardiovascular Diseases
This review explores the critical role of mitochondria in heart development and cardiovascular disease. It highlights how mitochondrial maturation during embryonic‐to‐postnatal transition, regulated by oxygen and metabolic changes, shapes cardiac structure and function.
Minghao Li +3 more
wiley +1 more source
Dietary strategies modulate the progression of diabetic cardiomyopathy by targeting oxidative stress, inflammation, mitochondrial dysfunction, and myocardial fibrosis. Specific nutrients and bioactive compounds, as well as caloric restriction, improve myocardial metabolism and redox balance, whereas ketogenic diets exert time‐dependent beneficial or ...
Wen‐hui Deng +9 more
wiley +1 more source
Editorial: Pannexin and connexin signaling in cell death and tissue health and disease
Marc Mesnil +2 more
doaj +1 more source
Dysferlin stabilizes membrane nanodomains of cardiomyocytes after myocardial infarction. [PDF]
Wegener JB +19 more
europepmc +1 more source
Pharmacological Separation of Mechanosensory Mechanisms in Rat Urinary Bladder Ex Vivo
ABSTRACT The local response of the bladder wall to stretch is believed to result from the coordinated activation of mechanosensitive ion channels located in the plasma membrane of the cells that form the wall's urothelial and detrusor smooth muscle (DSM) layers.
Igor B. Philyppov +4 more
wiley +1 more source
Toxicological evaluation of paracetamol and ibuprofen: genetic and hematological alterations in male albino mice. [PDF]
Elgingihy SM +5 more
europepmc +1 more source
pH‐Dependent Microenvironmental Ionic Signaling in Pancreatic Ductal Adenocarcinoma
ABSTRACT Aim Pancreatic ductal adenocarcinoma (PDAC) develops within a uniquely dynamic pH landscape shaped by substantial acid–base fluxes produced by the exocrine pancreas. Secretion of alkaline pancreatic juice, normally linked to digestion, produces intermittent acidifications of the pancreatic interstitium, which challenges epithelial and stromal ...
Albrecht Schwab +37 more
wiley +1 more source

