Results 151 to 160 of about 40,743 (260)

Bone marrow stem cell connexins: misconceptions and new insights. [PDF]

Blood
Singh AK, Rallis KS, Cancelas JA.
europepmc   +1 more source

MXene Bioinks for 3D Bioprinting: Design and Translation

Small, Volume 22, Issue 50, 7 September 2026.
This study establishes a comprehensive framework for MXene‐based bioinks in 3D bioprinting, highlighting the interplay between rheological engineering and electroactive hydrogels. By optimizing electrical percolation and mediated signaling, these formulations drive tissue‐specific biological outcomes and accelerated regeneration.
Begüm Sarac, Seydanur Yücer, Fatih Ciftci   +2 more
wiley   +1 more source

Correction: Santo et al. The Implications of Connexin 43 Deficiency During the Early Stages of Chemically Induced Mouse Colon Carcinogenesis. <i>Antioxidants</i> 2022, <i>11</i>, 2368. [PDF]

Antioxidants (Basel)
Santo SGE, da Silva TC, Vinken M, Cogliati B, Barbisan LF, Romualdo GR.   +5 more
europepmc   +1 more source

Sleep Deprivation, Cytokine Dysregulation, and the Risk of Cardiac Arrhythmia in Dogs

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Sleep deprivation triggers systemic inflammation in dogs, activating cytokine networks (IL‐6, TNF, IFN‐γ) and JAK–STAT signalling. Network and enrichment analyses reveal immune‐cardiac interactions linked to altered electrophysiology and arrhythmia risk.
Adithya Sethumadhavan, Arun HS Kumar
wiley   +1 more source

<i>Eimeria bovis</i>-infected host cell-bystander cell interactions are essential for effective macromeront formation. [PDF]

Front Cell Infect Microbiol
Fischer J, Rojas-Barón L, Hermosilla C, Taubert A.   +3 more
europepmc   +1 more source

Piezo1 Activation Rescues Anabolic Response to Mechanical Loading in Aged Bone via Connexin 43 Hemichannels

Aging Cell, Volume 25, Issue 9, September 2026.
Yoda1‐induced Piezo1 activation enhances Piezo1‐Cx43 interaction upon mechanical stimulation, triggering PI3K‐Akt signaling to drive Cx43 phosphorylation and hemichannel opening. These events elevate PGE2 release, suppress SOST expression in senescent osteocytes, and ultimately enhance bone anabolism on the endosteal surface.
Dezhi Zhao, Jiayue Fu, Han Liu, Shuting Liang, Mingming Song, Aining Zhang, Dong‐en Wang, Qianjin Guo, You Zhang, Jiawei Wu, Huiyun Xu   +10 more
wiley   +1 more source

Structure-based virtual screening for selective connexin hemichannel blockers: a historical perspective on the discovery of a small organic inhibitor. [PDF]

Front Pharmacol
Lagos CF, Vargas A, García A, Duarte Y, Yi C, Sáez JC.   +5 more
europepmc   +1 more source

AMPK‐mediated prevention of vascular dysfunction with metformin: Experimental and population‐based evidence

British Journal of Pharmacology, Volume 183, Issue 17, Page 5389-5406, September 2026.
Angiotensin II induces vascular inflammation, senescence, extracellular matrix (ECM) degradation and endothelial dysfunction, thus impairing SK+/IK+ channel function and reducing endothelial‐dependent hyperpolarisation (EDH). Metformin activates AMPK, increasing SK+/IK+ channel function and restoring vasorelaxation.
Soroush Mohammadi Jouabadi, Annika A. Jüttner, Annique Claringbould, Rene de Vries, Ingrid M. Garrelds, Usha Musterd‐Bhaggoe, Bruno H. Stricker, Maryam Kavousi, A. H. Jan Danser, Fariba Ahmadizar, Anton J. M. Roks   +10 more
wiley   +1 more source

Connexin 31.9 is expressed in human pancreatic endocrine beta cells, as well as in exocrine ductal epithelial and vascular endothelial cells. [PDF]

Biosci Rep
Pérez-Armendariz EM, Zacarías-Lara OJ, Revilla-Monsalve C, Page-Pérez ER, Hernández-Téllez B, Zarain-Herzberg Á, Flores-García CA, Arreola-Rosales R, E Gudiño-Zayas M.   +8 more
europepmc   +1 more source

Mitochondrial transfer in acute myeloid leukaemia and multiple myeloma: Mechanisms, consequences and potential therapeutic opportunities

The FEBS Journal, Volume 293, Issue 17, Page 5107-5120, September 2026.
Mitochondria can be transferred from bone marrow cells to cancer cells in acute myeloid leukaemia and multiple myeloma, boosting tumour energy production, growth, and drug resistance. This review highlights key transfer mechanisms and shows how targeting mitochondrial movement and dynamics may offer new therapeutic strategies to limit cancer ...
Ebubechukwu Nwarunma, Mark T. S. Williams   +1 more
wiley   +1 more source