Results 31 to 40 of about 25,696 (242)
Cellular Physiology and Biochemistry, 2016 Aims: Connexin 43 is one of the most potent gap junction proteins related to osteoblast differentiation and bone formation. We hypothesized that Connexin 43 is a significant factor in osteogenic differentiation in the posterior longitudinal ligament ...
Haisong Yang +6 more
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BMC Cardiovascular Disorders, 2006 Background Organ transplantation is presently often the only available option to repair a damaged heart. As heart donors are scarce, engineering of cardiac grafts from autologous skeletal myoblasts is a promising novel therapeutic strategy.
Kienast Yvonne +9 more
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Connexin43 and Ischemic Preconditioning [PDF]
Cardiovascular Research, 2004 Connexin43 (Cx43) is the essential protein to form hemichannels and gap junctions in the myocardium. The phosphorylation status of Cx43 which is regulated by a variety of protein kinases and phosphatases determines hemichannel and/or gap junction conductance and permeability.
Rainer, Schulz, Gerd, Heusch
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Reproductive Biology and Endocrinology, 2006 Background Prolonged labour is associated with greater morbidity and mortality for mother and child. Connexin 43 is a major myometrial gap junction protein found in human myometrium.
Malmström Anders +6 more
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Reproductive Biology and Endocrinology, 2008 Background Myometrial smooth myocytes contract as a result of electrical signalling via a process called excitation-contraction coupling. This process is understood in great detail at the cellular level but the generation and coordination of electrical ...
Van Lommel Alfons +6 more
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Connexin-43 Hemichannels Opened by Metabolic Inhibition [PDF]
Journal of Biological Chemistry, 1999 The cause of altered ionic homeostasis leading to cell death during ischemia and metabolic inhibition is unclear. Hemichannels, which are precursors to gap junctions, are nonselective ion channels that are permeable to molecules of less than Mr 1000.
S A, John +4 more
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Connexin 43 Hemichannels Are Permeable to ATP [PDF]
The Journal of Neuroscience, 2008 Astrocytes are electrically nonexcitable cells that communicate by means of Ca2+signaling. Long-distance intercellular Ca2+waves are initiated by release of ATP and activation of purinergic receptors on nearby cells. Previous studies have implicated connexin 43 (Cx43) in ATP release, but definitive proof that ATP exits through Cx43 hemichannels does ...
Jian, Kang +6 more
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Connexin Expression in Human Minor Salivary Glands: An Immunohistochemical Microscopy Study
Molecules, 2022 Connexins (Cxs) are transmembrane proteins involved in the formation of hemichannels and gap junctions (GJs). GJs are involved in various physiological functions, including secretion in glandular tissue. It has been demonstrated that Cx26, Cx32, and Cx43
Alessandra Falleni +11 more
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Osteocytic connexin 43 channels affect fracture healing
Journal of Cellular Physiology, 2019 AbstractThe cross‐talk between cells is very critical for moving forward fracture healing in an orderly manner. Connexin (Cx) 43‐formed gap junctions and hemichannels mediate the communication between adjacent cells and cells and extracellular environment. Loss of Cx43 in osteoblasts/osteocytes results in delayed fracture healing. For investigating the
Yunhe Chen +7 more
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Internal translation of the connexin 43 transcript [PDF]
Cell Communication and Signaling, 2014 Connexin 43 (Cx43), the most widely expressed gap junction protein, is associated with a number of physiological and pathological conditions. Many functions of Cx43 have been shown to be independent of gap junction formation and only require the expression of Cx43 C-terminal fragments.
Salat-Canela, Clàudia +4 more
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