Results 61 to 70 of about 195,400 (281)

Plasma exosome-derived connexin43 as a promising biomarker for melanoma patients

open access: yesBMC Cancer, 2023
Background To examine the levels of exosome-derived connexin 43 (Cx43) in plasma and estimate its forecast value in patients with melanoma. Methods We measured the plasma exosome-derived Cx43 levels in the plasma of 112 melanoma patients and 50 healthy ...
Yue Shen   +4 more
doaj   +1 more source

Effects of candesartan, an angiotensin II receptor type I blocker, on atrial remodeling in spontaneously hypertensive rats [PDF]

open access: yes, 2015
Hypertension-induced structural remodeling of the left atrium (LA) has been suggested to involve the renin–angiotensin system. This study investigated whether treatment with an angiotensin receptor blocker, candesartan, regresses atrial remodeling in ...
Choisy, Stéphanie C.   +5 more
core   +1 more source

Progress and Application of Multifunctional Hydrogel in Radioactive Skin Injury

open access: yesAdvanced Materials Interfaces, EarlyView.
This review examines healing challenges in radiation‐wound injuries, where ionizing radiation impairs immune and tissue repair processes. Hydrogels, with their biocompatibility, antimicrobial properties, and drug delivery capabilities, present a transformative solution. It compares hydrogel efficacy in radiation‐induced versus common wounds, highlights
Xinyue Cui   +5 more
wiley   +1 more source

Astrocyte Networks as Therapeutic Targets in Glaucomatous Neurodegeneration

open access: yesCells, 2021
Astrocytes are intimately involved in the response to neurodegenerative stress and have become an attractive target for the development of neuroprotective therapies. However, studies often focus on astrocytes as single-cell units.
Andrew M. Boal   +4 more
doaj   +1 more source

Spherical isochrone models revisited [PDF]

open access: yes, 2020
A short derivation of all isochrone models using complex ...
arxiv   +1 more source

Expression of connexins in human preimplantation embryos in vitro [PDF]

open access: yes, 2004
Intercellular communication via gap junctions is required to coordinate developmental processes in the mammalian embryo. We have investigated if the connexin (Cx) isoforms known to form gap junctions in rodent preimplantation embryos are also expressed ...
Bloor, D.J.   +6 more
core   +4 more sources

Advances in Microfluidic Cochlea‐On‐A‐Chip

open access: yesAdvanced Science, EarlyView.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen   +10 more
wiley   +1 more source

Antidepressants impact connexin 43 channel functions in astrocytes

open access: yesFrontiers in Cellular Neuroscience, 2016
Glial cells, and in particular astrocytes, are crucial to maintain neuronal microenvironment by regulating energy metabolism, neurotransmitter uptake, gliotransmission and synaptic development.
Tiffany eJeanson   +6 more
doaj   +1 more source

New Generalized Common Fixed Point Theorems for Three Transformations on a Vector Valued S-metric Spaces [PDF]

open access: yesarXiv, 2023
In this article, we demonstrate the common fixed point theorems for three transformations on vector S-metric space by utilizing weakly compatible and point of coincidence. Moreover, some of our results generalize the existing results in the literature.
arxiv  

Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng   +11 more
wiley   +1 more source

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