Results 81 to 90 of about 100,756 (281)

Prolonged consciousness disorder and brain-computer interface: a new paradigm of medicine-engineering convergence in neuromodulation

Chinese Journal of Contemporary Neurology and Neurosurgery
Accurate assessment and intervention for prolonged consciousness disorder remain critical challenges in neuroscience. Brain-computer interface (BCI) offers a novel pathway for diagnosis and treatment of consciousness disorder by decoding neural signals ...
YANG Yi, HE Qi-heng, CHAI Xiao-ke, ZHAO Ji-zong   +3 more
doaj   +1 more source

Dorsolateral Cervical Cord T2 Hyperintensity in KIF1C‐Related Disease (Spastic Paraplegia 58): Two Long‐Duration Cases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Pathogenic variants in KIF1C cause Spastic Paraplegia 58 (SPG58), typically presenting with cerebellar ataxia and spastic paraparesis. We report two unrelated patients with spastic paraparesis, cerebellar ataxia, and tremor. Whole‐exome sequence analysis identified novel homozygous variants in the motor domain of KIF1C (NM_006612.6): c.921G>A (
Akihiko Mitsutake, Masao Osaki, Takashi Matsukawa, Miho Osako, Chisen Takeuchi, Hiroyuki Ishiura, Jun Mitsui, Ryo Kurokawa, Harushi Mori, Yuji Takahashi, Jun Goto, Shoji Tsuji, Tatsushi Toda   +12 more
wiley   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis. [PDF]

J Int Med Res, 2022
Wang P, Cao W, Zhou H, Zhang HX, Zhang L, Liu L, Sui Y, Zhang Z, Yin X, Yang F, Kong L.   +10 more
europepmc   +1 more source

A Tree of Life? Multivariate logistic outcome-prediction in disorders of consciousness [PDF]

, 2019
Inga Steppacher, Peter Fuchs, M. Kaps, Fridtjof W. Nußbeck, Johanna Kißler   +4 more
openalex   +1 more source

Needs and Quality of Life of Caregivers of Patients with Prolonged Disorders of Consciousness [PDF]

, 2023
Olivia Gosseries, Caroline Schnakers, Audrey Vanhaudenhuyse, Charlotte Martial, Charlène Aubinet, Vanessa Charland‐Verville, Aurore Thibaut, Jitka Annen, Didier Ledoux, Steven Laureys, Charlotte Grégoire   +10 more
openalex   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source

The clinical complication scale of Fondazione Don Gnocchi for classifying clinical complications in patients with severe acquired brain injury: development and multicenter validation

Frontiers in Neurology
IntroductionPatients with severe acquired brain injury have a high risk of developing clinical complications that affect clinical outcome and rehabilitation program.
Anna Estraneo, Maria Rosaria Fiorentino, Tommaso Cibellis, Biagio Campana, Pietro Balbi, Valentina Carli, Elena Vatteroni, Guya Devalle, Francesco Mantelli, Mattia Villa, Alessandra Bianchi, Maria Concetta Costa, Marina Rossi, Angela Comanducci, Jorge Navarro, Alessandro Viganò, Agnese De Nisco, Francesca Draghi, Bahia Hakiki, Bahia Hakiki, Alfonso Magliacano   +20 more
doaj   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

Developing a data visualization tool for adults with disorders of consciousness: Qualitative analysis of user perspectives

Learning Health Systems
Introduction We report on the process of using a learning health systems (LHS) approach to design a data visualization dashboard to monitor the rehabilitation progress of patients with disorders of consciousness (DoC) after severe brain injury.
Alison M. Cogan, Shonali G. Gaudino, James E. Green II, Lewis E. Kazis, Mary D. Slavin, Jeffrey C. Schneider, Joseph T. Giacino   +6 more
doaj   +1 more source