Results 81 to 90 of about 3,798,930 (303)

Disruption in structural–functional network repertoire and time-resolved subcortical fronto-temporoparietal connectivity in disorders of consciousness

bioRxiv, 2021
Understanding recovery of consciousness and elucidating its underlying mechanism is believed to be crucial in the field of basic neuroscience and medicine. Ideas such as the global neuronal workspace and the mesocircuit theory hypothesize that failure of
R. Panda, A. Thibaut, A. López-González, A. Escrichs, M. Bahri, A. Hillebrand, G. Deco, S. Laureys, O. Gosseries, J. Annen, P. Tewarie   +10 more
semanticscholar   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Neuroimaging characterization of recovery of impaired consciousness in patients with disorders of consciousness

Neural Regeneration Research, 2019
Elucidation of critical brain areas or structures that are responsible for recovery of impaired consciousness in patients with disorders of consciousness is important because it can provide information that is useful when developing therapeutic ...
Sung Ho Jang, Young Hyeon Kwon
doaj   +1 more source

Disorders of Consciousness Associated With COVID-19

Neurology, 2021
Background and Objectives In patients with severe coronavirus disease 2019 (COVID-19), disorders of consciousness (DoC) have emerged as a serious complication.
David Fischer, S. Snider, M. Barra, W. R. Sanders, O. Rapalino, P. Schaefer, A. Foulkes, Yelena G. Bodien, B. Edlow   +8 more
semanticscholar   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The ethical relevance of the unconscious

Philosophy, Ethics, and Humanities in Medicine, 2017
Background Ethical analyses of disorders of consciousness traditionally focus on residual awareness. Going one step further, this paper explores the potential ethical relevance of the unawareness retained by patients with disorders of consciousness ...
Michele Farisco, Kathinka Evers
doaj   +1 more source

Risk factors for 2‐year mortality in patients with prolonged disorders of consciousness: An international multicentre study

European Journal of Neurology, 2021
Patients with prolonged disorders of consciousness (pDoC) have a high mortality rate due to medical complications. Because an accurate prognosis is essential for decision‐making on patients' management, we analysed data from an international multicentre ...
A. Estraneo, A. Magliacano, S. Fiorenza, R. Formisano, A. Grippo, E. Angelakis, H. Cassol, A. Thibaut, O. Gosseries, G. Lamberti, E. Noé, S. Bagnato, B. Edlow, C. Chatelle, N. Lejeune, V. Veeramuthu, M. Bartolo, D. Mattia, J. Toppi, N. Zasler, C. Schnakers, L. Trojano   +21 more
semanticscholar   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Psilocybin increases optimistic engagement over time: computational modelling of behaviour in rats

Translational Psychiatry
Psilocybin has shown promise as a novel pharmacological intervention for treatment of depression, where post-acute effects of psilocybin treatment have been associated with increased positive mood and decreased pessimism.
Elizabeth L. Fisher, Ryan Smith, Kyna Conn, Andrew W. Corcoran, Laura K. Milton, Jakob Hohwy, Claire J. Foldi   +6 more
doaj   +1 more source

Central nervous system manifestations in COVID‐19 patients: A systematic review and meta‐analysis

Brain and Behavior, 2021
Background At the end of December 2019, a novel respiratory infection, initially reported in China, known as COVID‐19 initially reported in China, and later known as COVID‐19, led to a global pandemic.
Shahrzad Nazari, Amirhossein Azari Jafari, Seyyedmohammadsadeq Mirmoeeni, Saeid Sadeghian, Mohammad Eghbal Heidari, Siavash Sadeghian, Farhad Assarzadegan, Seyed Mahmoud Puormand, Hamid Ebadi, Davood Fathi, Sahar Dalvand   +10 more
doaj   +1 more source