Results 81 to 90 of about 1,670,289 (294)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Brain endogenous feedback and degrees of consciousness

, 2012
We present a model able to account for the mechanisms supporting different degrees of consciousness. We support our proposal with recent evidence from brain morphology and physiology, which indicate that the central nervous system contains two parallel ...
Pereira Jr., Alfredo [UNESP], Carrara-Augustenborg, Claudia   +1 more
core  

Greater preserved baseline functional MRI connectivity in zolpidem responders compared to non-responders in patients with disorders of consciousness.

, 2019
peer reviewedIntroduction Zolpidem is commonly used as sleep inducer but is one of the few available pharmacological treatments for patients with disorders of consciousness (DOC).
Martial, Charlotte, Heine, Lizette, Bahri, Mohamed Ali, Charland-Verville, Vanessa, VANHAUDENHUYSE, Audrey, Ippoliti, Camilla, Aubinet, Charlène, Laureys, Steven, Gosseries, Olivia, Di Perri, Carol, Sanz, Leandro, Larroque, Stephen Karl, Carrière, Manon   +12 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

[Swallowing in disorders of consciousness].

Revue neurologique, 2014
Interest in studying swallowing disorders in patients with altered consciousness has increased over the past decade. Swallowing deficit is frequently encountered in severe brain-injured patients.Results of studies have highlighted different factors such as the delay between the injury and the treatment and the level of consciousness of these patients ...
Bicego, Aminata Yasmina, Lejoly, Kelly, Maudoux, Audrey, Lefèbvre, Philippe, Laureys, Steven, SchweizerSchweizer, Valérie, Diserens, K., FAYMONVILLE, Marie-Elisabeth, VANHAUDENHUYSE, Audrey   +8 more
openaire   +2 more sources

Consciousness of life sense at patients with neurotic disorders [PDF]

, 2013
Frankl said that consciousness of sense of life is the state of subjective satisfaction directed to values and connected with useful activity. This metaneed determinates mental health and development of personality.
Lucyna Bobkowicz-Lewartowska, Bobkowicz-Lewartowska, Lucyna   +1 more
core  

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

Pre- and post-therapy functional MRI connectivity in severe acute brain injury with suppression of consciousness: a comparative analysis to epilepsy features

Frontiers in Neuroimaging
Severe acute brain injury (SABI) with suppressed consciousness is a major societal burden, with early prognosis being crucial for life-and-death treatment decisions.
Emilio G. Cediel, Erika A. Duran, Jeffrey Laux, William Reuther, Olivia Leggio, Belfin Robinson, Varina L. Boerwinkle   +6 more
doaj   +1 more source

Large-Scale Brain Simulation and Disorders of Consciousness. Mapping Technical and Conceptual Issues

Frontiers in Psychology, 2018
Modeling and simulations have gained a leading position in contemporary attempts to describe, explain, and quantitatively predict the human brain’s operations. Computer models are highly sophisticated tools developed to achieve an integrated knowledge of
Michele Farisco, Michele Farisco, Jeanette H. Kotaleski, Jeanette H. Kotaleski, Kathinka Evers   +4 more
doaj   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source