Results 71 to 80 of about 1,467,463 (316)

Formally verified asymptotic consensus in robust networks [PDF]

open access: green, 2022
Mohit Tekriwal   +4 more
openalex   +1 more source

Unbeatable Consensus

open access: yesDistributed Computing, 2014
The unbeatability of a consensus protocol, introduced by Halpern, Moses and Waarts in 2001, is a stronger notion of optimality than the accepted notion of early stopping protocols. Using a novel knowledge-based analysis, this paper derives the first practical unbeatable consensus protocols in the literature, for the standard synchronous message-passing
Armando Castañeda   +2 more
openaire   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Expert Consensus on the Clinical Utilization of Ketamine and Its Isomers in Intensive Care Units

open access: yesIntensive Care Research
Analgesia and sedation are important treatment strategies in the intensive care unit (ICU). Due to the opioid crisis, opioid-sparing medications become the focus of clinical studies.
Zhiyong Peng   +3 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

How to reach a compromise solution on technical and non-structural flood control measures

open access: yesSoil and Water Research, 2014
Harmful impacts of floods are the result of an interaction between extreme hydrological events and environmental, social, and economic processes. Flood management should consider many diverse aspects and influences and an integrated approach to flood ...
Pavel KOVÁŘ   +3 more
doaj   +1 more source

Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conference [PDF]

open access: bronze, 1997
Norman L. Foster   +6 more
openalex   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Consenso 2012 da Sociedade Brasileira de Reumatologia para o tratamento da artrite reumatoide 2012 Brazilian Society of Rheumatology Consensus for the treatment of rheumatoid arthritis

open access: yesRevista Brasileira de Reumatologia, 2012
OBJETIVO: Elaborar recomendações para o tratamento da artrite reumatoide no Brasil. MÉTODO: Revisão da literatura com seleção de artigos baseados em evidência e opinião de especialistas da Comissão de Artrite Reumatoide da Sociedade Brasileira de ...
Licia Maria Henrique da Mota   +11 more
doaj   +1 more source

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