Results 151 to 160 of about 3,611,494 (288)

Conservation Biology [PDF]

Ecology, 1988
openaire   +2 more sources

Soil and cherry bacterial communities predict flavor on coffee farms

Scientific Reports
Coffee (Coffea arabica) is a popular beverage worldwide with increasing value placed on sensory qualities as specialty markets grow. Plant-associated microbiomes have emerged as a potential but poorly understood driver of coffee flavor that may interact ...
Steve Kutos, Ruth E. Bennett, Danilo Santos, Esteban Botero-Delgadillo, Carly R. Muletz-Wolz   +4 more
doaj   +1 more source

Evaluating conservation biology texts for bias in biodiversity representation. [PDF]

PLoS One, 2020
Stahl K, Lepczyk CA, Christoffel RA.
europepmc   +1 more source

Molecular sexing of degraded DNA from elephants and mammoths: a genotyping assay relevant both to conservation biology and to paleogenetics. [PDF]

Sci Rep, 2021
Aznar-Cormano L, Bonnald J, Krief S, Guma N, Debruyne R.   +4 more
europepmc   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Conservation Biology:

, 2014
Michael E. Soulé, Bruce A. Wilcox
  +5 more sources

Omics approaches for conservation biology research on the bivalve Chamelea gallina. [PDF]

Sci Rep, 2020
Carducci F, Biscotti MA, Trucchi E, Giuliani ME, Gorbi S, Coluccelli A, Barucca M, Canapa A.   +7 more
europepmc   +1 more source