Results 171 to 180 of about 342,303 (293)
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Background and Objectives: The Important Bird Areas (IBA) program is a science-based initiative to identify, conserve, and monitor sites that provide essential habitat for bird populations.
Watts, B. D.
core
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
De-extinction: how reviving the past is revolutionizing the future of conservation biology. [PDF]
Hutchison JC +7 more
europepmc +1 more source
The north-eastern escarpment of Madagascar has been deemed a global hotspot of biodiversity due to its high levels of endemic speciesbeing heavily threatened by accelerated deforestation rates and landscape changes.
Hett, Cornelia +4 more
core
How phagocytic cells kill bacteria: Lessons from a professional killer
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
The diversity of ignorance and the ignorance of diversity: origins and implications of "shadow diversity" for conservation biology and extinction. [PDF]
Turton-Hughes S, Holmes G, Hassall C.
europepmc +1 more source
The endemic Hawaiian wēkiu bug (Nysius wekiuicola) is a carnivorous scavenger that only inhabits volcanic cinder cones above ~3,500 m elevation on the mountain, Maunakea, Hawai‘i.
Kirkpatrick, Jessica Ann
core
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source

