Results 141 to 150 of about 644,259 (331)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Identifying shorebird conservation hotspots and restoration gaps in stopover sites: A perspective of ‘ecologically linked’ habitats

, 2023
Xiaowei Li, Xiyong Hou, Shan Kai, Yubin Liu, Yang Song, Xiaoli Wang, Peipei Du, Chao Fan   +7 more
openalex   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Habitat differentiation and conservation gap of Magnolia biondii, M. denudata, and M. sprengeri in China. [PDF]

PeerJ, 2019
Song C, Liu H.
europepmc   +1 more source

MOESM5 of What evidence exists on the impact of governance type on the conservation effectiveness of forest protected areas? Knowledge base and evidence gaps

, 2015
Biljana Macura, Laura Secco, Andrew S. Pullin   +2 more
openalex   +1 more source

Use of passive acoustic monitoring to fill knowledge gaps of fish global conservation status [PDF]

, 2023
Marta Bolgan, Éric Parmentier, Marta Picciulin, Louis Hadjioannou, Lucia Di Iorio   +4 more
openalex   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Identifying the Knowledge and Capacity Gaps in Southeast Asian Insect Conservation [PDF]

Xin Rui Ong, Benito C. Tan, Charlotte H. Chang, Nalini Puniamoorthy, Eleanor M. Slade   +4 more
openalex   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Gaps in the protection of the amphibians of Myanmar—threat status, endemism, protected area coverage and One Plan Approach conservation [PDF]

Marie Borgwerth, Carolin Scholten, Aung Ko Lin, Myint Kyaw Thura, Larry Lee Grismer, Thomas Ziegler, Dennis Rödder   +6 more
openalex   +1 more source