Results 121 to 130 of about 644,259 (331)

Lost in translation? Insights into caribou habitat selection from forest inventory data

FACETS, 2019
The gap between research and its implementation is an impediment to conservation of the environment. Translating science into actionable management and policy requires effective communication and collaboration among scientists, practitioners, and policy ...
Tyler D. Rudolph, Doug MacNearney, Laura Finnegan   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Habitat analysis and conservation priorities for the endangered spotted linsang in China

Global Ecology and Conservation
Small carnivores play vital roles in ecosystems, but their elusive nature makes data collection challenging. Infrared camera technology provides an effective solution to this issue.
Xijin Hu, Chencheng Zhang, Zufei Shu, Yingming Zhang, Buhang Li, Chengjin Chu   +5 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Bridging the Gap: Leveraging Student Engagement in Conservation Science

This paper approaches conservation science through the lens of education, prioritising conceptual exploration over empirical outcomes. Emphasising the limitations inherent in existing instruments and databases for Cultural Heritage samples, the paper advocates for a shift towards leveraging student involvement in addressing these challenges.
Kate Seymour, Haedeun Kim, Caroline Bouvier, Arleta Kezika, Danitsa Davis, Daan van Zutphen, Melania Janiak, Francesca Diederen, Lara Sofia Maus, Giuditta Perversi   +9 more
openaire   +2 more sources

Bridging the Gap: Community Conservancies in Namibia and Zimbabwe

, 2023
AbstractThe emergence of community-based natural resource management (CBNRM) approaches to wildlife conservation in southern Africa heralded great optimism towards the bridging of the gap between ‘fortress conservation’ and the welfare of local communities living adjacent to protected areas.
openaire   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Extinction risk and conservation gaps for Aloe (Asphodelaceae) in the Horn of Africa [PDF]

, 2019
Steven P. Bachman, Paul Wilkin, Tom Reader, Richard Field, Odile Weber, Inger Nordal, Sebsebe Demissew   +6 more
openalex   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source