Results 111 to 120 of about 374,356 (270)

Using conservation genetics to prioritise management options for an endangered songbird. [PDF]

Heredity (Edinb), 2023
Alves F, Banks SC, Edworthy M, Stojanovic D, Langmore NE, Heinsohn R.   +5 more
europepmc   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

A paired comparison of scat‐collecting versus scat‐swabbing methods for noninvasive recovery of mesocarnivore DNA from an arid environment

Wildlife Society Bulletin, 2015
Noninvasive DNA sampling from scats can provide powerful tools for wildlife research depending in large part on how scats are collected in the field. Preservation of scat in 95–100% ethanol can be highly effective, but not always practical.
Kathleen A. Miles, Michelle N. Holtz, Zachary T. Lounsberry, Benjamin N. Sacks   +3 more
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Landscape genetics reveal broad and fine‐scale population structure due to landscape features and climate history in the northern leopard frog (Rana pipiens) in North Dakota [PDF]

, 2018
Prehistoric climate and landscape features play large roles structuring wildlife populations. The amphibians of the northern Great Plains of North America present an opportunity to investigate how these factors affect colonization, migration, and current
Fisher, Justin D.L., Mushet, David M., Purcell, Kevin, Stockwell, Craig A., Waraniak, Justin M.   +4 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

A decade of GigaScience: A perspective on conservation genetics. [PDF]

Gigascience, 2022
O'Brien SJ.
europepmc   +1 more source

Conservation genetics in the marine realm [PDF]

, 1998
Techniques for DNA and protein assay make possible genetic studies on any species. In recent years, molecular methods have been applied to a number of conservation-relevant genetic issues for marine organisms ranging from zooplankton to whales.
Avise, JC
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Effects of individual and group factors on the social relationships of Budgerigars

Avian Research
Social animals often form dynamic relationships with group members, which have been associated with increased social learning, survival and reproductive success.
Xueqi Zhao, Jiangping Yu, Jie Su, Manxi Lu, Chunguang Dong, Xiyu Wang, Haitao Wang   +6 more
doaj   +1 more source