Results 91 to 100 of about 588,087 (304)

Telomere‐to‐Telomere Genomes Reveal that Multiscale Evolution Shapes the Largest Metabolic Arsenal of Diaporthe Fungi

open access: yesAdvanced Science, EarlyView.
This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li   +9 more
wiley   +1 more source

Monopoly power and distribution in fragmented markets : the case of groundwater [PDF]

open access: yes
Using data from Pakistan's Punjab, the authors examine monopoly power in the market for groundwater - irrigation water extracted using private tubewells - a market characterized by barriers to entry and spatial fragmentation.
Jacoby, Hanan G.   +2 more
core  

Work-family enrichment: it’s mediating role in the relationships between dispositional factors and job satisfaction [PDF]

open access: yes, 2015
The growing interest in understanding the interface of work and family roles, in particular work-family enrichment, and its antecedents and outcomes, has stimulated the development of a mediation model.
Ahmad, Aminah   +2 more
core  

Employees’ Financial Insecurity and Health: The Underlying Role of Stress and Work–Family Conflict Appraisals

open access: yes, 2018
Data from two longitudinal samples were utilized to elucidate underlying mechanisms of the well‐established relationship between financial insecurity and health outcomes, stemming from the theoretical rationale of conservation of resources and cognitive ...
Matthews, Russell A.   +2 more
core   +1 more source

Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli

open access: yesAdvanced Science, EarlyView.
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch   +4 more
wiley   +1 more source

Resources and Technologies [PDF]

open access: yes
This Working Paper joint two previous articles by the authors: The economic theory of exhaustible natural resources, in “Enciclopedia degli Idrocarburi”, vol. IV, Istituto della Enciclopedia Treccani, Roma, 2008, pp.
Alberto Quadrio Curzio   +2 more
core  

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

open access: yesAdvanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore   +20 more
wiley   +1 more source

Money or Nothing: The Adverse Environmental Consequences of Uncompensated Land Use Control [PDF]

open access: yes, 2008
The conventional wisdom holds that requiring compensation for environmental land use controls would severely limit environmental protection efforts. There are increasing reasons to question this assumption.
Adler, Jonathan H
core   +1 more source

Evaluating the Utilities of Foundation Models in Single‐Cell Data Analysis

open access: yesAdvanced Science, EarlyView.
This study delivers the first systematic, task‐level evaluation of single‐cell foundation models across eight core analytical tasks. By benchmarking 10 leading models with the scEval framework, it reveals where foundation models truly add value, where task‐specific methods still dominate, and provides concrete, reproducible guidelines to steer the next
Tianyu Liu   +4 more
wiley   +1 more source

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