Results 111 to 120 of about 543,710 (291)

Evaluation of a solidary academic-pedagogical project in virtual graduate programs

Frontiers in Education
The consolidation of virtual education as a strategic modality in postgraduate training requires rigorous evaluations of its relevance from the student perspective.
Kris Evelin Ortiz-Ordoñez, Diana Carolina Burbano-Gonzalez, Jorge Andrés Suarez-Muñoz   +2 more
doaj   +1 more source

Inconsistencies in Reported Employment Characteristics among Employed Stayers [PDF]

The paper deals with measurement error, and its potentially distorting role, in information on industry and professional status collected by labour force surveys.
Bassi, Francesca, Padoan, Alessandra, Trivellato, Ugo   +2 more
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

RESEARCH ON BEARING FAULT DIAGNOSIS BASED ON CEEMDAN FUZZY ENTROPY AND CONVOLUTIONAL NEURAL NETWORK (MT)

Jixie qiangdu, 2023
In order to extract the fault information of rolling bearing vibration signals under strong noise coverage and improve the accuracy of fault diagnosis and classification, based on the theory of fuzzy entropy（FE）, a new method of complete ensemble ...
XIAO JunQing, JIN JiangTao, LI Chun, XU ZiFei, SUN Kang   +4 more
doaj  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Construct validity of the PHQ-9 in university students in Colombia: A Rasch analysis approach

Medicina Clínica y Social
Introduction: The Patient Health Questionnaire 9 (PHQ-9) is one of the most widely used screening instruments for major depressive episodes.
Carlos Arturo Cassiani-Miranda, Orlando Scoppetta, María Alejandra Barrios-Villadiego, Andrés Felipe Tirado-Otálvaro, Andrea Carolina Duran-Bedoya   +4 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Independence clustering (without a matrix)

, 2017
The independence clustering problem is considered in the following formulation: given a set $S$ of random variables, it is required to find the finest partitioning $\{U_1,\dots,U_k\}$ of $S$ into clusters such that the clusters $U_1,\dots,U_k$ are ...
Ryabko, Daniil
core