Results 51 to 60 of about 1,335,503 (297)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Banking consolidation in Nigeria, 2000-2010 [PDF]
This study examines the Nigerian banking consolidation process using a dynamic panel for the period 2000-2010. The Arellano and Bond (1991) dynamic GMM approach is adopted to estimate a cost function taking into account the possible endogeneity of the ...
Barros, CP, Caporale, GM
core +5 more sources
To study the influence of consolidation stress ratio and stress history on 1-D consolidation permeability of saturated clay, one-dimensional consolidation permeability tests were carried out with GDS triaxial device.
Le Zhang +3 more
doaj +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Effect of Bentonite on the Coefficient of Consolidation of Soil
Bentonite is a fine clay, usually occurring as a byproduct of atmospheric weathering of volcanic ash. It is widely known for its capabilities of high absorption of moisture, and swelling, as a result of moisture contact. Bentonite has a crystalline structure with the main constituent as montmorillonite which has a dual ...
openaire +1 more source
Soft soil was found in several areas in Indonesia, one of them is in Kalimantan Island, which the soft soil in the island mostly formed by Alluvium. One of the characteristics of the soft soil is that they are likely still in under consolidating stage.
Edwin Lie, Aswin Lim
openaire +1 more source
(Table 4) Coefficient of consolidation and permeability for DSDP Leg 96 holes
(Table 4) Coefficient of consolidation and permeability for DSDP Leg 96 ...
William Bryant (6886685) +7 more
core +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

