Results 71 to 80 of about 1,335,503 (297)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Coefficient of consolidation of sandy clay
, 2014 Consolidation is a major issue of geotechnical engineering due to its implications on ground settlement. Efficacy of remedial measures against excessive consolidation relies on understanding of factors affecting coefficient of consolidation. This project
Kusnadi, Andhi Wijaya Harja
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
A Contingency View of Consolidation Systems [PDF]
, 2009 A consolidation system is a type of an accounting information system that aims to facilitate the consolidation process of organisations that are comprised of a collection of entities, but that are required to produce one set of consolidated financial ...
SMITH, PIETER,RETIEF +1 more
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Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Stress-dependent consolidation characteristics of marine clay in the Northern Arabian Gulf
Ain Shams Engineering Journal, 2018 The main objective of this paper is to study the variation of the coefficient of consolidation (Cv) with stress level for the marine clay in the Northern Arabian Gulf.
Tamer Elkateb
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Dinamika Rekayasa, 2008 Soft clay is kind of problem in building and highway foundation design. This type of soils, have low coefficient consolidation (Cv) parameter. This condition will cause that soils have very long duration in consolidation process.
Arwan Apriyono +2 more
doaj
LAND OWNERSHIP CONSOLIDATION IN THE CONTEXT OF SUSTAINABLE DEVELOPMENT [PDF]
Land consolidation is seen today as an important instrument which facilitates the improvement of the agricultural infrastructure in general and the development of agriculture by creating a structure of exploitation in accordance with the market demands ...
Laura CIOBANU +3 more
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