Results 71 to 80 of about 122,080 (304)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Constellation

open access: yes
Title inscribed upper left.Faint sketch below Constellation sketch.Gift, J.P.
Waud, Alfred R. 1828-1891, artist.
core   +4 more sources

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Hybrid Constellation Shaping 64QAM Based on Hexagonal Lattice of Constellation Subset

open access: yes, 2023
Increasing demand for higher-speed and large-capacity data communications has driven the development of constellation shaping technology. This paper proposes a hybrid constellation shaping scheme for 64-quadrature amplitude modulation (64QAM) based on ...
Qinghua Tian   +7 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

The Needle in the Haystack: Uncovering the First Whale Shark (Rhincodon typus) Aggregation in the Coral Sea

open access: yesEcology and Evolution
Aggregations are key events, supporting critical ecological and biological functions in many species. For highly mobile and elusive species, aggregations often provide the only feasible opportunities for research.
Ingo B. Miller   +16 more
doaj   +1 more source

Autonomous satellite constellation for enhanced Earth coverage using coupled selection equations

open access: yes, 2013
This paper presents a novel solution to the problem of autonomous task allocation for a self-organising constellation of small satellites in Earth orbit.
Colombo, Camilla   +3 more
core  

Design of a micro-satellite constellation for communication

open access: yes, 2013
The purpose of this paper is to present a low Earth orbit constellation which provides a communication function over a region centered in Taiwan, with radii of 500 km, 1000 km, 1500 km, 2000 km and 2500 km, and orbit altitudes of 800 km and 1500 km ...
Ma, Der-Ming; Hong, Zuu-Chang; Lee, Tzung-Hang; Chang, Bo-Jyun   +1 more
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Self-organising low Earth orbit constellations for Earth observation

open access: yes, 2014
This paper presents a novel method of manipulating the spatial pattern of a fractionated micro-satellite constellation in Low Earth Orbit. The method developed allows satellites to manipulate the longitudinal position of their ground-tracks over the ...
McInnes, Colin, Mushet, Garrie
core  

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