Results 161 to 170 of about 124,966 (247)

The correlation between traditional Chinese medicine constitutions and chronic kidney disease-associated pruritus among hemodialysis patients in Macau. [PDF]

Medicine (Baltimore)
Chuang YC, Zhang Y, Chuang KH, Wang X, Wu J.   +4 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

A scale for assessing the health of children aged 3-6 years in China: development and validation of the TCM constitution scale (3-6 years). [PDF]

Front Public Health
Li W, Dong S, Li Z, Chen S, Cai Y, Bai MH, Chen JX, Wang J.   +7 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Association of thermal perceptions, metabolic rate, clothing, and local skin temperature in people with cold constitution in air-conditioned office environments. [PDF]

J Physiol Anthropol
Biswas BK, Ishii K, Watanabe Y, Li J, Tan Y, Dempoya A, Takeuchi S, Lee SI, Iwamura T, Konoshita S, Wakabayashi H.   +10 more
europepmc   +1 more source

The fundamental traditional Chinese medicine constitution theory serves as a crucial basis for the development and application of food and medicine homology products

Food & Medicine Homology
Jing Guo, Xue-Ying Zhao, Ya-Xin Cao, Jing-Han Jia, Yan-Fei Zheng, Wen-Long Sun, Ling-Ru Li   +6 more
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Dysbiosis of gut microbiota in children with functional constipation and damp-heat constitution: a cross-sectional multi-omics analysis. [PDF]

Sci Rep
Zhao H, Lu X, Ye Y, Li W, Ye H, Long Z, Zhang X, Wu J, Wang J.   +8 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Traditional Chinese Medicine Constitution and Cognitive Frailty in Older Adults: Prediction Models and Sleep-Quality Mediation Pathway from a Multicenter Study in China. [PDF]

Clin Interv Aging
Qiao M, Yang S, Ma Y, Chen C, Xu M, Gan H, Wu W.   +6 more
europepmc   +1 more source