Results 171 to 180 of about 127,679 (266)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Effects of a comprehensive management mode for overweight/obesity based on mobile internet technology and traditional Chinese medicine constitution theory: a randomized controlled trial. [PDF]

Front Nutr
Chen X, Duan J, Duan R, Wang Y, Jiang H.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Bulk Versus Surface Regulation of Cyclic Superelasticity in LPBF-Fabricated NiTi Alloy. [PDF]

Materials (Basel)
Yang Y, Wei T, Su C, Wan J, Nie X, Yang J.   +5 more
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Application of machine learning methods in prediction of the body constitution types and transformation trends of traditional Chinese medicine: from the datasets of questionnaire survey on elderly people in Southwest China. [PDF]

Front Med (Lausanne)
Huo Y, Wang J, He Y, Zhao Y, Wang F, Zhang M.   +5 more
europepmc   +1 more source

The Political concept of the Constitution and the Concepts of Hidden Constitution, Modest Constitution and, Behind –the-Scenes” Constitution [PDF]

Proceedings of the International Conference on Advanced Research in Social Sciences and Humanities, 2019
openaire   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Development of a predictive model for high-risk infertility based on TCM constitution and syndrome: a secondary analysis. [PDF]

Front Med (Lausanne)
Gao Z, Miao X, Feng J, Yang T, Hu Y, Shi B, Guan M, Liu Y, He Z, Wu X.   +9 more
europepmc   +1 more source