Results 191 to 200 of about 127,679 (266)

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

Correlation Between Prakriti (Body Constitution) and Severity of Structural Alterations in the Lungs of Patients With SARS-CoV-2: Protocol for a Retrospective Cross-Sectional Study. [PDF]

JMIR Res Protoc
Gudadhe R, Sawarkar G, Deshpande A.
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Swallowing-related cough and health status of old adults: Results from a nationwide cross-sectional study

Chinese Medical Journal
Huai-Yu Wang, Minghua Bai, Jinwei Wang, Zhuqing Li, Ji Wang, Qi Wang, Xiangxiang Pan   +6 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Prevalence of traditional Chinese medicine body constitutions in a large community-based study in Hangzhou, China. [PDF]

Chin Med
Wu YH, Wang J, Bai MH, Wang Q, Myers A, Gao P, Delzell E, Huang D, Yang F, He W, Zhu S, Hsing AW.   +11 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Application of a Large Visual Language Model on Tongue Image Description Generation and Physical Constitution Reasoning in Traditional Chinese Medicine (TongueVLM): Model Development and Validation Study. [PDF]

JMIR Med Inform
Peng C, Gao J, Yang N, Wang Y, Chen R, Dong C.   +5 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Exploring the Prakriti (Body Constitution) of Stroke Patients: A Scoping Review From an Ayurvedic Perspective. [PDF]

Cureus
S S, Sharma SV, Sindhu A, K AB, M H, Kukkupuni SK, Vishnuprasad CN, Chandrachari KP, Shouche Y, Garady L, Shankar P.   +10 more
europepmc   +1 more source