Results 101 to 110 of about 35,760 (296)

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Temperature and Strain Rate Dependence on the Tensile Mechanical Properties, Constitutive Equations, and Fracture Mechanisms of MarBN Steel. [PDF]

Materials (Basel), 2023
Jiang Y, Zou T, Liu M, Cai Y, Wang Q, Wang Y, Pei Y, Zhang H, Liu Y, Wang Q.   +9 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

A methodology to quantify effects of constitutive equations on safety analysis using integral effect test data

Nuclear Engineering and Technology
To improve the predictive capability of a nuclear thermal hydraulic safety analysis code by developing a better constitutive equation for individual phenomenon has been the general research direction until now.
ChoHwan Oh, Jeong Ik Lee
doaj   +1 more source

Mechanical Models of Pattern and Form in Biological Tissues: The Role of Stress-Strain Constitutive Equations. [PDF]

Bull Math Biol, 2021
Villa C, Chaplain MAJ, Gerisch A, Lorenzi T.   +3 more
europepmc   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

A modification of the convective constraint release mechanism in the molecular stress function model giving enhanced vortex growth

, 2006
YesThe molecular stress function model with convective constraint release (MSF with CCR) constitutive model [J. Rheol. 45 (2001), 1387] is capable of fitting all viscometric data for IUPAC LDPE, with only two adjustable parameters (with difference found ...
Wagner, M.H., Olley, Peter
core   +1 more source

An energy residual-based approach to gradient effects within the mechanics of generalized continua

Journal of the Mechanical Behavior of Materials, 2012
Generalized continua exhibiting gradient effects are addressed through a method grounded on the energy residual (ER)-based gradient theory by the first author and coworkers.
Polizzotto Castrenze, Pisano Aurora A.
doaj   +1 more source

Constitutive Equations for Analyzing Stress Relaxation and Creep of Viscoelastic Materials Based on Standard Linear Solid Model Derived with Finite Loading Rate. [PDF]

Polymers (Basel), 2022
Lin CY, Chen YC, Lin CH, Chang KV.
europepmc   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source