Results 111 to 120 of about 24,902,874 (336)

Extended concept of representative directions to describe inelastic behaviour of electrospun polymers [PDF]

, 2019
The concept of representative directions allows one to generalize onedimensional uniaxial material models to more general constitutive equations, suitable for arbitrary multi-axial loading scenarios.
Shutov, Alexey V.
core  

On the selection of Johnson-Cook constitutive model parameters for Ti-6Al-4V using three types of numerical models of orthogonal cutting

, 2015
Johnson-Cook constitutive model is still the most used model in metal cutting simulation, although several drawbacks reported in the literature. A high number of Johnson-Cook model parameters can be found in the literature for the same work material. One
Yancheng Zhang, J. Outeiro, Tarek Mabrouki   +2 more
semanticscholar   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Mechanical constitutive model of stand off damping composites layered rubber core under wide strain rates

Scientific Reports
To characterize the dynamic mechanical response and vibration-damping characteristics of a layered rubber core (LRC) in a stand-off damping structure, a series of experiments were carried out and a continuous power-law variable fractional-order Kelvin ...
Zhangda Zhao, Wenjun Meng, Bijuan Yan, Guansen Qiao, Yuan Qin, Yao Wang, Tao Yang, Hong Ren   +7 more
doaj   +1 more source

Ballistic Performance of Thermoplastic Fiber-Reinforced Metal Laminates Subjected to Impact Loadings

Applied Sciences
This paper aims to predict the damage and fracture behavior of thermoplastic fiber-reinforced metal laminates (TFMLs) under ballistic impact loadings.
Yan Zeng, Chunguang Li, Hong Zheng, Yijun Liu   +3 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Comparison of phenomenological and physical-based constitutive material models for Cr17Mn17Mo3NiN low nickel stainless steel

Materials Research Express
Phenomenological and physical-based constitutive models for the Cr17Mn17Mo3NiN low nickel stainless steel were developed based on the true stress–strain curves acquired from isothermal uniaxial compression tests.
Gun Song Jang, Kyong Ho Sim
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Arrhenius constitutive model of FV520B steel

Metalurgija
To investigate the thermoplastic deformation behavior of FV520B steel, the Gleeble-3800 thermal simulation test machine is used to perform hot compression test on FV520B steel. Select a deformation temperature of 900 °C - 1 050 °C, set the strain rate to
J. Deng, L. W. Chen, B. Y. Cui, Y. P. Li, H. C. Ji   +4 more
doaj  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source