Results 51 to 60 of about 736,297 (294)

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

A thermoviscoplastic model with damage for simultaneous hot/cold forging analysis [PDF]

, 2013
A constitutive model is presented for simultaneous hot/cold forming processes of steels. The phenomenological material theory is based on an enhanced rheological model and accounts temperature dependently for nonlinear hardening, thermally activated ...
Bröcker, C., Matzenmiller, A.
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Bursts in a fiber bundle model with continuous damage

, 2001
We study the constitutive behaviour, the damage process, and the properties of bursts in the continuous damage fiber bundle model introduced recently. Depending on its two parameters, the model provides various types of constitutive behaviours including ...
A. Delaplace, A. E. Naaman, A. G. Evans, A. G. Evans, A. Garcimartín, A. Guarino, A. Hansen, A. Petri, B. D. Coleman, B. K. Chakrabarti, C. Moukarzel, D. G. Harlow, D. G. Harlow, D. Krajcinovic, D. Sornette, D. Sornette, F. Hild, F. Kun, F. Kun, Ferenc Kun, H. E. Daniels, Hans. J. Herrmann, I. J. Beyerlein, I. L. Menezes-Sobrinho, L. Moral, M. Kloster, P. C. Hemmer, P. Duxbury, P. L. Leath, R. L. Smith, Raul Cruz Hidalgo, S. J. Zhou, S. L. Phoenix, S. L. Phoenix, S. M. Spearing, S. Roux, S. Zapperi, S. Zapperi, S. Zapperi, T. Kanada, W. A. Curtin, W. A. Curtin, W. A. Curtin, W. A. Curtin, W. A. Curtin, W. I. Newman, W. I. Newman, Y. Moreno   +47 more
core   +1 more source

Transition regime analytical solution to gas mass flow rate in a rectangular micro channel [PDF]

, 2012
We present an analytical model predicting the experimentally observed gas mass flow rate in rectangular micro channels over slip and transition regimes without the use of any fitting parameter.
Dadzie, Kokou, Dongari, Nishanth
core   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

High Temperature Mechanical Constitutive Modeling of a High-Nb TiAl Alloy

Journal of Aeronautical Materials, 2018
Uniaxial tensile, low cycle fatigue, fatigue-creep interaction and creep experiments of a novel high-Nb TiAl alloy (i.e. Ti-45Al-8Nb-0.2W-0.2B-0.02Y (atom fraction/%)) were conducted at 750℃ to obtain its tested data and curves.
DONG Chengli, YU Huichen, JIAO Zehui, KONG Fantao, CHEN Yuyong   +4 more
doaj   +1 more source

A Coupled Elastoplastic Damage Dynamic Model for Rock

Shock and Vibration, 2021
Rock dynamic constitutive model plays an important role in understanding dynamic response and addressing rock dynamic problems. Based on elastoplastic mechanics and damage mechanics, a dynamic constitutive model of rock coupled with elastoplastic damage ...
Xuelong Hu, Ming Zhang, Xiangyang Zhang, Min Tu, Zhiqiang Yin, Haifeng Ma, Minke Duan   +6 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Stress-strain Constitutive Models Along the Grain of Original Bamboo Based on Classification

BioResources
To establish the constitutive model of original bamboo, the tensile and compressive tests along the grain of original bamboo were investigated. The original bamboo was graded according to the elastic modulus, and a stress-strain constitutive model of ...
Zhili Cui, Zhenhua Jiao, Wei Tong, Pan Li   +3 more
doaj   +2 more sources