Results 71 to 80 of about 257,652 (258)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Method to determine the optimal constitutive model from spherical indentation tests

Results in Physics, 2018
The limitation of current indentation theories was investigated and a method to determine the optimal constitutive model through spherical indentation tests was proposed.
Tairui Zhang, Shang Wang, Weiqiang Wang
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Comparison of phenomenological and physical-based constitutive material models for Cr17Mn17Mo3NiN low nickel stainless steel

Materials Research Express
Phenomenological and physical-based constitutive models for the Cr17Mn17Mo3NiN low nickel stainless steel were developed based on the true stress–strain curves acquired from isothermal uniaxial compression tests.
Gun Song Jang, Kyong Ho Sim
doaj   +1 more source

NEML2: An efficient and modular multiphysics constitutive modeling library for hybrid computing environments

SoftwareX
This paper presents NEML2, an open-source, high-performance library developed for constitutive material modeling, designed to support the flexible and modular development of models for complex material behavior.
Tianchen Hu, Mark C. Messner
doaj   +1 more source

The Managerial Constitution: The Convergence of Constitutional and Corporate Governance Models

SSRN Electronic Journal, 2013
This paper proposes the concept of the “Managerial Constitution”, which advocates the convergence between constitutional and corporate governance models. Such concept is based on the interpretation of certain features of the Brazilian Constitution enacted in 1988 that may serve as a model for modern democracies in developing countries.
openaire   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Ballistic Performance of Thermoplastic Fiber-Reinforced Metal Laminates Subjected to Impact Loadings

Applied Sciences
This paper aims to predict the damage and fracture behavior of thermoplastic fiber-reinforced metal laminates (TFMLs) under ballistic impact loadings.
Yan Zeng, Chunguang Li, Hong Zheng, Yijun Liu   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source